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ST段抬高型心肌梗死老年患者血管内成像的使用率及结果

Utilization Rate and Outcomes of Intravascular Imaging in Elderly Patients Presenting With ST-Elevation Myocardial Infarction.

作者信息

Elzeneini Mohammed, Betageri Omkar, Kamisetty Sujay R, Assaf Yazan, Elgendy Islam Y, Shah Khanjan B

机构信息

Division of Cardiovascular Medicine, University of Florida, Gainesville, FL, United States of America.

Division of Cardiovascular Medicine, Maine Medical Center, Portland, ME, United States of America.

出版信息

Cardiovasc Revasc Med. 2023 Jan;46:90-95. doi: 10.1016/j.carrev.2022.08.004. Epub 2022 Aug 6.

Abstract

BACKGROUND

Elderly patients presenting with ST-elevation myocardial infarction (STEMI) represent a vulnerable population with comorbid conditions and complex coronary anatomy. We aimed to describe the utilization rate and outcomes of intravascular imaging to guide percutaneous coronary intervention (PCI) in this population.

METHODS

The Nationwide Readmissions Database was queried for all hospitalizations for STEMI involving PCI from 2018 to 2019. Hospitalizations were stratified by patient age into a younger cohort <75 years (mean age 58.7 ± 9.5 years) and an older cohort ≥75 years. Propensity score-weighed regression analysis was used to identify the association of intravascular imaging with in-hospital mortality, 90-day all-cause readmission, and readmission for myocardial infarction (MI).

RESULTS

A total of 299,619 STEMI PCI hospitalizations were included. Intravascular imaging was utilized less frequently in the older cohort (6.8 % vs 7.8 %, odds ratio [OR] 0.87, 95 % CI 0.82-0.92, p < 0.001). In both cohorts, intravascular imaging was more likely to be used with anterior STEMI, complex PCI, mechanical support, and thrombectomy. Propensity score analysis showed the use of intravascular imaging was associated with lower in-hospital mortality in both cohorts (OR 0.60, 95 % CI 0.52-0.68, p < 0.001 in the younger cohort and OR 0.61, 95 % CI 0.51-0.72, p < 0.001 in the older cohort). There was no difference in 90-day all-cause readmission or readmission for MI with intravascular imaging.

CONCLUSIONS

Intravascular imaging during STEMI PCI is associated with lower in-hospital mortality regardless of age. Further studies are needed to understand the low utilization rates especially among elderly patients.

摘要

背景

患有ST段抬高型心肌梗死(STEMI)的老年患者是一个具有合并症和复杂冠状动脉解剖结构的弱势群体。我们旨在描述血管内成像在该人群中指导经皮冠状动脉介入治疗(PCI)的使用率和结果。

方法

查询2018年至2019年全国再入院数据库中所有涉及PCI的STEMI住院病例。住院病例按患者年龄分层为年龄小于75岁的较年轻队列(平均年龄58.7±9.5岁)和年龄大于等于75岁的较老年队列。倾向评分加权回归分析用于确定血管内成像与住院死亡率、90天全因再入院率以及心肌梗死(MI)再入院率之间的关联。

结果

共纳入299,619例STEMI PCI住院病例。血管内成像在老年队列中的使用频率较低(6.8%对7.8%,优势比[OR]0.87,95%可信区间0.82 - 0.92,p < 0.001)。在两个队列中,血管内成像更可能用于前壁STEMI、复杂PCI、机械支持和血栓切除术。倾向评分分析显示,在两个队列中,使用血管内成像均与较低的住院死亡率相关(较年轻队列中OR 0.60,95%可信区间0.52 - 0.68,p < 0.001;较老年队列中OR 0.61,95%可信区间0.51 - 0.72,p < 0.001)。血管内成像在90天全因再入院率或MI再入院率方面没有差异。

结论

无论年龄大小,STEMI PCI期间的血管内成像均与较低的住院死亡率相关。需要进一步研究以了解特别是老年患者中使用率较低的情况。

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