Tanyildiz Burak, Oklar Murat, Günaydın Nesrin T, Kandemir Baran
Department of Ophthalmology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.
Saudi J Ophthalmol. 2022 Jul 11;36(1):95-101. doi: 10.4103/sjopt.sjopt_251_21. eCollection 2022 Jan-Mar.
The aim of this study was to analyze the trends in the major indications and types of keratoplasty over a 15-year period and to determine the effect of the coronavirus disease-2019 (COVID-19) pandemic on the selection of corneal transplant recipients at a tertiary referral center in Turkey.
We retrospectively reviewed the data of patients who underwent keratoplasty at the center from January 2006 to March 2021. The keratoplasty indications and types of surgery were evaluated after classification into three groups (period I - January 2006-December 2012; period II - January 2013-March 2020; COVID-19 period - April 2020-March 2021).
A total of 5016 corneal transplants were performed in 3862 patients. Lamellar keratoplasty (LK) techniques were found to demonstrate a statistically significantly increasing trend compared to penetrating keratoplasty in the period between 2006 and 2021 (χ = 240.55, < 0.001). The top 4 indications over the 15-year period were aphakic/pseudophakic bullous keratopathy (BK) (1105, 22%), keratoconus (1085, 21.6%), regraft (1084, 21.6%), and keratitis (645, 12.8%). The most common keratoplasty indication during the COVID-19 period was regraft (27, 54.0%), followed by BK (13, 26.0%) and corneal perforation (5, 10%).
BK was the most common keratoplasty indication at our clinic during the 15-year period. LK rates have been found to increase in recent years, although still not reaching the rates of developed countries. There was a marked decrease in the number of keratoplasties during the COVID-19 pandemic and patients requiring urgent keratoplasty or those who suffered from a painful eye were prioritized.
本研究旨在分析15年间角膜移植术的主要适应证和类型的变化趋势，并确定2019年冠状病毒病（COVID-19）大流行对土耳其一家三级转诊中心角膜移植受者选择的影响。
我们回顾性分析了2006年1月至2021年3月在该中心接受角膜移植术患者的数据。将角膜移植术的适应证和手术类型分为三组进行评估（第一阶段——2006年1月至2012年12月；第二阶段——2013年1月至2020年3月；COVID-19阶段——2020年4月至2021年3月）。
共对3862例患者实施了5016例角膜移植手术。2006年至2021年期间，与穿透性角膜移植术相比，板层角膜移植术（LK）技术呈现出统计学上显著的上升趋势（χ = 240.55， < 0.001）。15年间前4位的适应证依次为无晶状体/人工晶状体眼大泡性角膜病变（BK）（1105例，22%）、圆锥角膜（1085例，21.6%）、再次移植（1084例，21.6%）和角膜炎（645例，12.8%）。COVID-19期间最常见的角膜移植适应证是再次移植（27例，54.0%），其次是BK（13例，26.0%）和角膜穿孔（5例，10%）。
在15年期间，BK是我们诊所最常见的角膜移植适应证。近年来LK率有所上升，尽管仍未达到发达国家的水平。COVID-19大流行期间角膜移植手术数量显著减少，急需角膜移植手术的患者或眼部疼痛的患者被优先考虑。
