Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
J Korean Med Sci. 2022 Aug 15;37(32):e250. doi: 10.3346/jkms.2022.37.e250.
The aim of our study was to investigate the incidence of and risk factors for coronavirus disease 2019 (COVID-19) in patients with non-tuberculous mycobacterial-pulmonary disease (NTM-PD). A total of 3,866 patients with NTM-PD were retrospectively identified from a single center. Compared to the general population of Korea, patients with NTM-PD had a substantially increased age-standardized incidence of COVID-19 from January 2020 to February 2021 (2.1% vs. 0.2%). The odds of being infected with COVID-19 was particularly higher in patients who received treatment for NTM-PD than in those who did not receive treatment for NTM-PD (adjusted odd ratio = 1.99, 95% confidence interval = 1.09-3.64, = 0.026). Patients with NTM-PD might be regarded as a high-risk group for COVID-19 and may need a more proactive preventive strategy for COVID-19 and other pandemics in the future.
本研究旨在探讨非结核分枝杆菌肺病（NTM-PD）患者中 2019 年冠状病毒病（COVID-19）的发病率和危险因素。从一家中心回顾性确定了 3866 例 NTM-PD 患者。与韩国普通人群相比，2020 年 1 月至 2021 年 2 月，NTM-PD 患者 COVID-19 的年龄标准化发病率明显更高（2.1% vs. 0.2%）。与未接受 NTM-PD 治疗的患者相比，接受 NTM-PD 治疗的患者感染 COVID-19 的几率更高（调整比值比=1.99，95%置信区间=1.09-3.64，=0.026）。NTM-PD 患者可能被视为 COVID-19 的高危人群，未来可能需要针对 COVID-19 和其他大流行采取更积极的预防策略。
