Paterson D J, Wood G A, Marshall R N, Morton A R, Harrison A B
J Appl Physiol (1985). 1987 May;62(5):1767-71. doi: 10.1152/jappl.1987.62.5.1767.
Breathing frequency (f) is often reported as having an integer-multiple relationship to limb movement (entrainment) during rhythmic exercise. To investigate the strength of this coupling while running under hypoxic conditions, two male Caucasians and four male Nepalese porters were tested in the Annapurna region of the Himalayas at altitudes of 915, 2,135, 3,200, 4,420, and 5,030 m. In an additional study in a laboratory at sea level, three male and four female subjects inspired various O2-N2 mixtures [fraction of inspired O2 (FIO2) = 20.93, 17.39, 14.40, 11.81%] that were administered in a single-blind randomized fashion during a treadmill run (40% FIO2 maximum O2 consumption). Breathing and gait signals were stored on FM tape and later processed on a PDP 11/73 computer. The subharmonic relationships between these signals were determined from Fourier analysis (power spectrum), and the coincidence of coupling occurrence was statistically modeled. Entrainment decreased linearly during increasing hypoxia (P less than 0.01). Moreover, a significant linear increase in f occurred during hypoxia (P less than 0.05), whereas stride frequency and metabolic rate remained constant, suggesting that hypoxic-induced increases in f decreased the degree of entrainment.
呼吸频率（f）通常被报道在有节奏的运动过程中与肢体运动（夹带）存在整数倍关系。为了研究在低氧条件下跑步时这种耦合的强度，两名男性高加索人和四名男性尼泊尔搬运工在喜马拉雅山安纳布尔纳地区海拔915、2135、3200、4420和5030米处进行了测试。在海平面实验室的另一项研究中，三名男性和四名女性受试者吸入不同的O₂-N₂混合气体[吸入氧分数（FIO₂）=20.93、17.39、14.40、11.81%]，这些混合气体在跑步机跑步（40% FIO₂最大耗氧量）期间以单盲随机方式给予。呼吸和步态信号存储在调频磁带上，随后在PDP 11/73计算机上进行处理。这些信号之间的次谐波关系通过傅里叶分析（功率谱）确定，耦合发生的一致性进行了统计建模。在低氧程度增加时夹带呈线性下降（P<0.01）。此外，在低氧期间f出现显著线性增加（P<0.05），而步频和代谢率保持不变，这表明低氧诱导的f增加降低了夹带程度。
