Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Aalborg, Denmark.
Expert Rev Cardiovasc Ther. 2022 Sep;20(9):761-772. doi: 10.1080/14779072.2022.2112667. Epub 2022 Aug 19.
Risk factors for retinal vein occlusion have been extensively studied, with varying population sizes. Smaller populations result in less certain measures of associations. The present review included studies with a relevant population size to identify clinically relevant risk factors for retinal vein occlusion. Understanding the risk factors of retinal vein occlusion is important for the management of these patients.
A comprehensive literature review was conducted through a systematic literature search in PubMed and Embase. Additional studies were selected from cross references in the assessed studies. Weighted effect measures were calculated for all included risk factors.Risk factors associated with retinal vein occlusion included cardiovascular diseases, eye diseases, systemic diseases, medical interventions, and sociodemographic factors.
This review provided an extensive overview of a wide variety of risk factors increasing the risk of developing retinal vein occlusion. The severity of the identified risk factors indicated that these patients have been in contact with the health care system before their retinal vein occlusion event. Therefore, the clinical course for patients with retinal vein occlusion may benefit from a multidisciplinary collaboration between ophthalmologists and especially cardiologists.
已经对视网膜静脉阻塞的危险因素进行了广泛研究，研究人群的规模大小不一。较小的人群会导致关联的衡量标准不太确定。本综述纳入了具有相关人群规模的研究，以确定视网膜静脉阻塞的临床相关危险因素。了解视网膜静脉阻塞的危险因素对于这些患者的治疗非常重要。
通过在 PubMed 和 Embase 中进行系统的文献检索，进行了全面的文献综述。还从评估研究的参考文献中选择了其他研究。对所有纳入的危险因素均计算了加权效应量。与视网膜静脉阻塞相关的危险因素包括心血管疾病、眼部疾病、系统性疾病、医疗干预和社会人口因素。
本综述广泛概述了多种增加视网膜静脉阻塞风险的危险因素。所确定的危险因素的严重程度表明，这些患者在视网膜静脉阻塞事件之前已经接触过医疗保健系统。因此，视网膜静脉阻塞患者的临床病程可能受益于眼科医生和心脏病专家之间的多学科合作。
