Călugăru D
Clinica de Oftalmologie Cluj-Napoca.
Oftalmologia. 2011;55(2):27-37.
Risk factors for the occurrence of central retinal vein occlusion are to a certain extent similar to those of cardiovascular diseases (e.g. arteriosclerosis, arterial systemic hypertension, diabetes mellitus, dislipidemia). Hyperhomocysteinemia is an essential risk factor for arteriosclerosis intervening also directly in the local mechanism of causing venous and arterial occlusions. Ocular hypertension and glaucoma are risk factors significantly associated with pathogenesis of central retinal vein occlusion. Therapy with anticoagulants and platelet anti-aggregating agents exposes the patient to developing central retinal vein occlusion influencing also adversely the visual outcome without having any evidence of protective or beneficial effect.
视网膜中央静脉阻塞发生的危险因素在一定程度上与心血管疾病(如动脉硬化、系统性动脉高血压、糖尿病、血脂异常)的危险因素相似。高同型半胱氨酸血症是动脉硬化的重要危险因素,也直接参与导致静脉和动脉阻塞的局部机制。高眼压和青光眼是与视网膜中央静脉阻塞发病机制显著相关的危险因素。使用抗凝剂和血小板抗聚集剂进行治疗会使患者面临发生视网膜中央静脉阻塞的风险,这也会对视力预后产生不利影响,且没有任何证据表明其具有保护或有益作用。