Northwestern University Feinberg School of Medicine, Department of Emergency Medicine, Chicago, IL, USA.
Grapefruit, Parsippany, NJ, USA.
Public Health. 2022 Sep;210:160-162. doi: 10.1016/j.puhe.2022.06.030. Epub 2022 Aug 13.
Determine if a school-based Test-to-Stay (TTS) program designed to minimize learning loss reduced the incidence of COVID-19 in a US primary school district.
Observational, simple summary analysis of attendance and effectiveness of a TTS program implemented in a California school district.
Retrospective analysis of nested medical and demographic data. Survival curves were plotted using a cumulative hazard function to compare the probability of infection among close contacts exposed at school at different points of time between participants who participated in TTS versus those who did not participate in TTS. A Cox proportional hazards regression model with time-dependent covariates was used to estimate the association of TTS status with the incidence of SARS-CoV-2 infection.
Univariate Cox regression analysis revealed that after adjustment, enrollment in TTS was negatively correlated with the risk of SARS-CoV-2 infection (hazard ratio 0.096; 95% confidence interval [CI], 0.024-0.390; P < 0.001).
TTS is an effective component of a layered protection strategy to prevent COVID-19 transmission in schools and communities, while minimizing the loss of in-person instruction in primary schools.
确定一项以减少学习损失为目标的基于学校的 Test-to-Stay（TTS）计划是否降低了美国一个小学区的 COVID-19 发病率。
对加利福尼亚学区实施的 TTS 计划的出勤情况和效果进行观察性、简单总结分析。
对嵌套的医疗和人口统计学数据进行回顾性分析。使用累积风险函数绘制生存曲线，以比较在不同时间点暴露于学校的密切接触者中，参加 TTS 的参与者与未参加 TTS 的参与者之间感染的概率。使用具有时变协变量的 Cox 比例风险回归模型来估计 TTS 状态与 SARS-CoV-2 感染发生率之间的关联。
单变量 Cox 回归分析显示，调整后，参加 TTS 与 SARS-CoV-2 感染的风险呈负相关（风险比 0.096；95%置信区间 [CI]，0.024-0.390；P<0.001）。
TTS 是防止学校和社区 COVID-19 传播的分层保护策略的有效组成部分，同时最大限度地减少小学面授课程的损失。
