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压力治疗期间人烧伤后增生性皮肤的力学特性

Mechanical characterisation of human postburn hypertrophic skin during pressure therapy.

作者信息

Clark J A, Cheng J C, Leung K S, Leung P C

出版信息

J Biomech. 1987;20(4):397-406. doi: 10.1016/0021-9290(87)90047-9.

Abstract

Postburn hypertrophic scar commonly occurs among the Chinese resulting from serious burn injuries. A non-invasive method of preventing and controlling such scars is using pressure therapy. Its mechanical properties are used as a quantitative indicator for scar assessment and maturation. The non-linear properties of the skin tissue are characterised in this study by a modulus of elasticity and a percentage extension (strain) at load intensities of 20, 40 and 100 g. The latter is a measure of the scar extensibility while the former the scar stiffness. A correlation is obtained between the clinical scar grading and these mechanical properties. Altogether 300 individual measurements were made on fifteen Chinese patients of ages ranging from 18 to 44 with burn injuries of superficial to whole skin thickness burns which necessitated surgical graft procedures. This in vivo study of the mechanical properties of hypertrophic scar tissue lasted 2 yr.

摘要

烧伤后增生性瘢痕在中国因严重烧伤而常见。一种预防和控制此类瘢痕的非侵入性方法是使用压力疗法。其力学性能用作瘢痕评估和成熟度的定量指标。本研究通过弹性模量和在20、40和100克负荷强度下的伸长百分比(应变)来表征皮肤组织的非线性特性。后者是瘢痕伸展性的度量,而前者是瘢痕硬度的度量。临床瘢痕分级与这些力学性能之间存在相关性。对15名年龄在18至44岁之间、烧伤程度从浅度到全层皮肤烧伤且需要手术植皮的中国患者共进行了300次个体测量。这项关于增生性瘢痕组织力学性能的体内研究持续了2年。

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