Research Unit for Nursing and Healthcare, Department of Public Health, Health, Aarhus University, Aarhus, Denmark.
Protac A/S, Skanderborg, Denmark.
JBI Evid Synth. 2023 Jan 1;21(1):200-206. doi: 10.11124/JBIES-21-00403.
The objective of this review is to identify and synthesize the best available evidence on how adult patients experience living with depression-related insomnia. In particular, the review will examine the experiences related to pharmacological and non-pharmacological interventions to improve sleep.
Approximately 80% to 90% of patients with depression have insomnia, which is associated with substantial personal and social costs. Despite these costs, insomnia is often underdiagnosed and viewed as a symptom that disappears when depression abates. However, research indicates that insomnia and depression are overlapping but distinct disorders. Thus, it is important to treat both disorders simultaneously, as improving sleep may, in turn, ease core symptoms of depression. Optimal care and treatment rely on patients' experiences of insomnia and their attitudes toward treatment options. Therefore, it is important to synthesize evidence of patients' experiences of living with insomnia, and the experiences of pharmacological and non-pharmacological sleep interventions, to understand the consequences of insomnia and to optimize sleep interventions.
This systematic review will synthesize qualitative studies exploring how adults with depression experience living with insomnia and how they experience pharmacological or non-pharmacological sleep interventions. Both inpatient and outpatient populations will be considered.
Databases to be searched include MEDLINE, Embase, CINAHL, PsycINFO, Cochrane Database of Systematic Reviews, Cochrane CENTRAL, SveMed+, Scopus, and Web of Science Core Collection. Google Scholar and ProQuest Dissertations and Theses will be searched for unpublished studies. Studies in English, German, Danish, Swedish, and Norwegian will be included. Databases will be searched from their inception to the present date. All studies will be screened against the inclusion criteria and critically appraised for methodological quality. Findings will be pooled using meta-aggregation, and a ConQual Summary of Findings will be presented.
PROSPERO CRD42021276048.
本综述旨在确定并综合现有最佳证据，以了解患有与抑郁相关的失眠症的成年患者的体验。特别是，本综述将研究与改善睡眠相关的药物和非药物干预措施的体验。
大约 80%至 90%的抑郁症患者存在失眠，这会带来巨大的个人和社会成本。尽管存在这些成本，但失眠常常被漏诊，并被视为抑郁症缓解时消失的症状。然而，研究表明，失眠和抑郁症是相互重叠但又不同的疾病。因此，同时治疗这两种疾病非常重要，因为改善睡眠可能会反过来缓解抑郁症的核心症状。最佳护理和治疗依赖于患者对失眠的体验及其对治疗选择的态度。因此，综合患者对失眠的体验以及对药物和非药物睡眠干预措施的体验的证据，了解失眠的后果，并优化睡眠干预措施非常重要。
本系统综述将综合探索患有抑郁症的成年人如何体验失眠以及他们如何体验药物或非药物睡眠干预措施的定性研究。将考虑住院和门诊人群。
将搜索的数据库包括 MEDLINE、Embase、CINAHL、PsycINFO、Cochrane 系统评价数据库、Cochrane 中心、SveMed+、Scopus 和 Web of Science 核心合集。将在 Google Scholar 和 ProQuest Dissertations and Theses 中搜索未发表的研究。纳入英语、德语、丹麦语、瑞典语和挪威语的研究。将从数据库创建开始一直搜索到当前日期。将根据纳入标准筛选所有研究，并对其进行方法学质量的批判性评估。使用元聚合汇总研究结果，并呈现 ConQual 总结的发现。
PROSPERO CRD42021276048。
