Artificial Intelligence and Machine Learning in Patient Blood Management: A Scoping Review.

Machine learning (ML) and artificial intelligence (AI) are widely used in many different fields of modern medicine. This narrative review gives, in the first part, a brief overview of the methods of ML and AI used in patient blood management (PBM) and, in the second part, aims at describing which fields have been analyzed using these methods so far. A total of 442 articles were identified by a literature search, and 47 of them were judged as qualified articles that applied ML and AI techniques in PBM. We assembled the eligible articles to provide insights into the areas of application, quality measures of these studies, and treatment outcomes that can pave the way for further adoption of this promising technology and its possible use in routine clinical decision making. The topics that have been investigated most often were the prediction of transfusion (30%), bleeding (28%), and laboratory studies (15%). Although in the last 3 years a constantly increasing number of questions of ML in PBM have been investigated, there is a vast scientific potential for further application of ML and AI in other fields of PBM.