Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Sci Rep. 2022 Aug 17;12(1):13952. doi: 10.1038/s41598-022-18258-w.
This study aimed to establish a nomogram for the prediction of cancer-specific survival (CSS) of CRC patients with synchronous LM. The final prognostic nomogram based on prognostic factors was evaluated by concordance index (C-index), time-dependent receiver operating characteristic curves, and calibration curves. In the training and validation groups, the C-index for the nomogram was 0.648 and 0.638, and the AUC was 0.793 and 0.785, respectively. The high quality of the calibration curves in the nomogram models for CSS at 1-, 3-, and 5-year was observed. The nomogram model provided a conventional and useful tool to evaluate the 1-, 3-, and 5-year CSS of CRC patients with synchronous LM.
本研究旨在建立一个列线图，用于预测同时性肝转移（LM）的 CRC 患者的癌症特异性生存（CSS）。基于预后因素的最终预测列线图通过一致性指数（C 指数）、时间依赖性接收者操作特征曲线和校准曲线进行评估。在训练组和验证组中，列线图的 C 指数分别为 0.648 和 0.638，AUC 分别为 0.793 和 0.785。观察到列线图模型在 CSS 1 年、3 年和 5 年的校准曲线具有较高的质量。该列线图模型为评估同时性 LM 的 CRC 患者的 1 年、3 年和 5 年 CSS 提供了一种常规且有用的工具。
