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3T质子磁共振波谱在脊髓中的评估——初步结果

Evaluation of 3T proton MR spectroscopy in the spinal cord - preliminary results.

作者信息

Wawrzyniak Pawel, Hebda Anna, Heinze Sylwia, Bobek-Billewicz Barbara

机构信息

The Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland.

The Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, Poland.

出版信息

Pol J Radiol. 2022 Jul 8;87:e375-e380. doi: 10.5114/pjr.2022.118194. eCollection 2022.

DOI:10.5114/pjr.2022.118194
PMID:35979148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9373865/
Abstract

PURPOSE

H-magnetic resonance spectroscopy (H-MRS) is a non-invasive technique that provides information on tissue metabolism and biochemistry. Because of technical difficulties, this method is rarely used in spinal cord examination. The main goal of this study was to develop a routine protocol for MRS of intramedullary lesions.

MATERIAL AND METHODS

A H-MRS protocol was set on a group of healthy volunteers. Forty-eight spectra were acquired in total. Thirty of them were acquired in cervical spinal cord, and the remaining 18 spectra were acquired in the thoracic spinal cord.

RESULTS

In H-MRS of the spinal cord one of the most important problems is small voxel size. Mean voxel size in this study was 7 × 9 × 29 mm, which is much smaller than in brain examinations. Finally, almost 60% of spectra were of acceptable quality in volunteer examinations, which enabled the subsequent examinations.

CONCLUSIONS

Challenges of spinal cord spectroscopy were discussed, and the ability of providing additional diagnostic information was proven.

摘要

目的

氢磁共振波谱(H-MRS)是一种提供组织代谢和生物化学信息的非侵入性技术。由于技术难题,该方法在脊髓检查中很少使用。本研究的主要目的是制定一种用于髓内病变磁共振波谱检查的常规方案。

材料与方法

为一组健康志愿者制定了H-MRS方案。共采集了48个波谱。其中30个在颈髓采集,其余18个波谱在胸髓采集。

结果

在脊髓的H-MRS检查中,最重要的问题之一是体素尺寸小。本研究中的平均体素尺寸为7×9×29毫米,远小于脑部检查中的体素尺寸。最后,在志愿者检查中,近60%的波谱质量可接受,这使得后续检查得以进行。

结论

讨论了脊髓波谱检查的挑战,并证明了其提供额外诊断信息的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/cbd3cb3bf524/PJR-87-47511-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/201bbf250eb7/PJR-87-47511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/b9413c8abdd7/PJR-87-47511-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/f210cd210e9b/PJR-87-47511-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/cbd3cb3bf524/PJR-87-47511-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/201bbf250eb7/PJR-87-47511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/b9413c8abdd7/PJR-87-47511-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/f210cd210e9b/PJR-87-47511-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8427/9373865/cbd3cb3bf524/PJR-87-47511-g004.jpg

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本文引用的文献

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The Application of Human Spinal Cord Magnetic Resonance Spectroscopy to Clinical Studies: A Review.人类脊髓磁共振波谱在临床研究中的应用:综述
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Non-water-suppressed proton MR spectroscopy improves spectral quality in the human spinal cord.非水抑制质子磁共振波谱可提高人体脊髓的光谱质量。
Magn Reson Med. 2013 May;69(5):1253-60. doi: 10.1002/mrm.24387. Epub 2012 Jun 28.
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Measurement of glycine in a brain and brain tumors by means of 1H MRS.采用 1H MRS 技术测量脑部和脑肿瘤中的甘氨酸。
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Quantitative cervical spinal cord 3T proton MR spectroscopy in multiple sclerosis.多发性硬化症患者颈椎脊髓的 3T 质子磁共振波谱定量分析。
AJNR Am J Neuroradiol. 2010 Jan;31(1):180-4. doi: 10.3174/ajnr.A1738. Epub 2009 Sep 3.
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Quantitative magnetic resonance spectroscopy in the entire human cervical spinal cord and beyond at 3T.3T下对整个人类颈脊髓及以外区域进行定量磁共振波谱分析。
Magn Reson Med. 2008 Jun;59(6):1250-8. doi: 10.1002/mrm.21578.
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