3T质子磁共振波谱在脊髓中的评估——初步结果
Evaluation of 3T proton MR spectroscopy in the spinal cord - preliminary results.
作者信息
Wawrzyniak Pawel, Hebda Anna, Heinze Sylwia, Bobek-Billewicz Barbara
机构信息
The Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland.
The Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, Poland.
出版信息
Pol J Radiol. 2022 Jul 8;87:e375-e380. doi: 10.5114/pjr.2022.118194. eCollection 2022.
PURPOSE
H-magnetic resonance spectroscopy (H-MRS) is a non-invasive technique that provides information on tissue metabolism and biochemistry. Because of technical difficulties, this method is rarely used in spinal cord examination. The main goal of this study was to develop a routine protocol for MRS of intramedullary lesions.
MATERIAL AND METHODS
A H-MRS protocol was set on a group of healthy volunteers. Forty-eight spectra were acquired in total. Thirty of them were acquired in cervical spinal cord, and the remaining 18 spectra were acquired in the thoracic spinal cord.
RESULTS
In H-MRS of the spinal cord one of the most important problems is small voxel size. Mean voxel size in this study was 7 × 9 × 29 mm, which is much smaller than in brain examinations. Finally, almost 60% of spectra were of acceptable quality in volunteer examinations, which enabled the subsequent examinations.
CONCLUSIONS
Challenges of spinal cord spectroscopy were discussed, and the ability of providing additional diagnostic information was proven.
目的
氢磁共振波谱（H-MRS）是一种提供组织代谢和生物化学信息的非侵入性技术。由于技术难题，该方法在脊髓检查中很少使用。本研究的主要目的是制定一种用于髓内病变磁共振波谱检查的常规方案。
材料与方法
为一组健康志愿者制定了H-MRS方案。共采集了48个波谱。其中30个在颈髓采集，其余18个波谱在胸髓采集。
结果
在脊髓的H-MRS检查中，最重要的问题之一是体素尺寸小。本研究中的平均体素尺寸为7×9×29毫米，远小于脑部检查中的体素尺寸。最后，在志愿者检查中，近60%的波谱质量可接受，这使得后续检查得以进行。
结论
讨论了脊髓波谱检查的挑战，并证明了其提供额外诊断信息的能力。
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