Ning Xiaoying, Zhang Yanfei, Wang Wei, Yan Huling, Xia Yumin
Department of Dermatology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Psychol Res Behav Manag. 2022 Aug 11;15:2107-2116. doi: 10.2147/PRBM.S370445. eCollection 2022.
Vitiligo is a common, acquired depigmenting disorder. The pathogenesis is not clear, neuropsychological factors may be involved. Vitiligo will affect the individual's physical and psychological health, leading to different levels of psychological behavior problems. However, there are few research on psychological symptoms in patients with vitiligo in China.
Adult patients with vitiligo were selected in convenient sampling method from March 2019 to November 2019 from the dermatology clinic. They were evaluated by the DLQI (Dermatology Life Quality Index), SCL-90 (Symptom Checklist-90), SADS (Social Avoidance and Distress Scale) and MCMQ (Medical Coping Modes Questionnaire).
The DLQI score was 7.56 ± 6.11, which was in the third level. The SCL-90 score of patients with vitiligo was 136.44 ± 39.19, significantly higher than the Chinese norms ( < 0.05), and it mainly manifested as interpersonal sensitivity, depression, anxiety and phobia, which may be affected by the patient's gender, marital status, severity of disease, stage and location of skin lesions. The total score of SADS in patients was 10.30 ± 6.38. The total score and scores in all dimensions of SADS were significantly higher than the Chinese norms (all < 0.05), which were related with the patient's gender, educational attainment, severity, type and stage of skin lesions. For MCMQ, the facing score was significantly lower than the Chinese norms ( < 0.05), and the avoiding and yielding scores were significantly higher than the Chinese norms (all < 0.05).
In China, vitiligo affects the patient's quality of life to varying degrees, resulting in a series of psychological and behavioral problems. We should actively concern and improve the psychological health status and behavior of patients, and multidisciplinary treatment strategies and education about vitiligo should be given to the patients.
白癜风是一种常见的获得性色素脱失性疾病。其发病机制尚不清楚，可能涉及神经心理因素。白癜风会影响个体的身心健康，导致不同程度的心理行为问题。然而，我国对白癜风患者心理症状的研究较少。
采用方便抽样法，选取2019年3月至2019年11月在皮肤科门诊就诊的成年白癜风患者。采用皮肤病生活质量指数（DLQI）、症状自评量表（SCL-90）、社交回避及苦恼量表（SADS）和医学应对方式问卷（MCMQ）对其进行评估。
DLQI评分为7.56±6.11，处于第三级别。白癜风患者的SCL-90评分为136.44±39.19，显著高于国内常模（P<0.05），主要表现为人际关系敏感、抑郁、焦虑和恐惧，可能受患者性别、婚姻状况、疾病严重程度、皮肤病变分期及部位影响。患者SADS总分10.30±6.38。SADS总分及各维度得分均显著高于国内常模（均P<0.05），与患者性别、文化程度、严重程度、皮肤病变类型及分期有关。对于MCMQ，面对维度得分显著低于国内常模（P<0.05），回避和屈服维度得分显著高于国内常模（均P<0.05）。
在我国，白癜风不同程度地影响患者生活质量，导致一系列心理和行为问题。应积极关注并改善患者的心理健康状况及行为，给予患者多学科治疗策略及白癜风相关教育。
