Department of Medicine, Dermatology Unit, Ahmadu Bello University, Zaria, Nigeria.
Department of Medicine, Immunology Unit, Ahmadu Bello University, Zaria, Nigeria.
Niger Postgrad Med J. 2021 Jul-Sep;28(3):169-174. doi: 10.4103/npmj.npmj_579_21.
Vitiligo is an acquired pigmentary disorder of the skin and mucous membranes which manifests as white macules and patches due to selective loss of melanocytes. This condition can affect the patients' psychology, leading to an impairment of quality of life (QOL). Recently, much attention is been given to the emotional and psychological issues in the affected subjects.
This was to assess the QOL impairment among Nigerian patients with vitiligo using a disease-specific quality of life index questionnaire (VitiQoL).
Seventy seven adults aged 18 years and above with vitiligo attending the Dermatology Clinic of a tertiary health center were included in this cross-sectional study. The QOL was assessed using the vitiligo quality of life questionnaire (VitiQoL). Disease severity was assessed using Vitiligo Area Severity Index (VASI).
The mean age of the study participants was 38.97 ± 13.2 years, comprising of 32 (41.6%) and 45 (58.4%) females. Almost half of the vitiligo patients belong to the lower socioeconomic class, 37 (48.1%). The mean age of first onset of vitiligo was 33.5 ± 14.84 years, with 32 (41.6%) of the participants having age of first onset between 24 and 42 years. The mean VitiQoL score was 30.51 ± 15.74 (range 3-64). There was a significant relationship between VASI score and VitiQoL (P = 0.036, r = 0.517). Other factors such as age, gender, socioeconomic status, disease activity, family history of vitiligo, duration of the disease and educational attainment were significantly associated with VitiQoL score (P < 0.05).
QOL is impaired significantly in Nigerian patients with vitiligo. Focusing on patient's QOL is an essential aspect in the management of patients with vitiligo.
白癜风是一种获得性皮肤和黏膜色素沉着障碍，由于黑素细胞选择性丧失，表现为白色斑片和斑块。这种情况会影响患者的心理，导致生活质量（QOL）受损。最近，人们越来越关注受影响人群的情绪和心理问题。
本研究旨在使用专门的生活质量指数问卷（VitiQoL）评估尼日利亚白癜风患者的生活质量受损情况。
这项横断面研究纳入了 77 名年龄在 18 岁及以上、在一家三级保健中心皮肤科就诊的成年白癜风患者。使用白癜风生活质量问卷（VitiQoL）评估生活质量。使用白癜风面积严重指数（VASI）评估疾病严重程度。
研究参与者的平均年龄为 38.97 ± 13.2 岁，其中 32 名（41.6%）和 45 名（58.4%）为女性。将近一半的白癜风患者属于较低的社会经济阶层，为 37 名（48.1%）。白癜风首次发病的平均年龄为 33.5 ± 14.84 岁，其中 32 名（41.6%）参与者首次发病年龄在 24 至 42 岁之间。平均 VitiQoL 得分为 30.51 ± 15.74（范围 3-64）。VASI 评分与 VitiQoL 之间存在显著关系（P = 0.036，r = 0.517）。其他因素，如年龄、性别、社会经济地位、疾病活动度、白癜风家族史、疾病持续时间和教育程度，与 VitiQoL 评分显著相关（P < 0.05）。
尼日利亚白癜风患者的生活质量明显受损。关注患者的生活质量是白癜风患者管理的一个重要方面。
