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食管颗粒细胞瘤:一例报告。

Esophageal granular cell tumor: A case report.

作者信息

Chen Ya-Lan, Zhou Jing, Yu Hui-Ling

机构信息

Department of Gastroenterology, the Affiliated Hospital of Hebei University, Baoding 071000, Hebei Province, China.

Department of Gastroenterology, Wangdu County Hospital, Baoding 071000, Hebei Province, China.

出版信息

World J Clin Cases. 2022 Jul 6;10(19):6543-6547. doi: 10.12998/wjcc.v10.i19.6543.

Abstract

BACKGROUND

Esophageal granular cell tumor (eGCT) is a relatively rare, usually benign neoplasm of the neuroectoderm. It is derived from Schwann cells. Clinical symptoms of this disease are non-specific. However, the most common presenting symptom is dysphagia, which is mostly misdiagnosed as esophageal polyps under gastroscopy, yet it has a 2% chance of forming cancers. We report the case of a 52-year-old woman with solitary eGCT, then analysed retrospectivelyanalyze the clinical features and elucidate on the reduction of misdiagnosis and missed diagnosis.

CASE SUMMARY

A 52-year-old woman was diagnosed with "esophageal granulossoma" after esophagoscopy, which was mistaken for eGCT.

CONCLUSION

eGCT diagnosis depends on characteristic pathomorphologies and detection of the S-100 protein. Endoscopic mucosal resection is the preferred therapeutic method.

摘要

背景

食管颗粒细胞瘤(eGCT)是一种相对罕见的、通常为良性的神经外胚层肿瘤。它起源于施万细胞。该疾病的临床症状不具有特异性。然而,最常见的症状是吞咽困难,在胃镜检查下大多被误诊为食管息肉,但它有2%的癌变几率。我们报告一例52岁患有孤立性eGCT的女性病例,然后回顾性分析其临床特征并阐明减少误诊和漏诊的方法。

病例摘要

一名52岁女性在食管镜检查后被诊断为“食管颗粒瘤”,该病例被误诊为eGCT。

结论

eGCT的诊断依赖于特征性的病理形态学及S-100蛋白的检测。内镜下黏膜切除术是首选的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e907/9294910/eab1570594b0/WJCC-10-6543-g001.jpg

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