Chen Ya-Lan, Zhou Jing, Yu Hui-Ling
Department of Gastroenterology, the Affiliated Hospital of Hebei University, Baoding 071000, Hebei Province, China.
Department of Gastroenterology, Wangdu County Hospital, Baoding 071000, Hebei Province, China.
World J Clin Cases. 2022 Jul 6;10(19):6543-6547. doi: 10.12998/wjcc.v10.i19.6543.
Esophageal granular cell tumor (eGCT) is a relatively rare, usually benign neoplasm of the neuroectoderm. It is derived from Schwann cells. Clinical symptoms of this disease are non-specific. However, the most common presenting symptom is dysphagia, which is mostly misdiagnosed as esophageal polyps under gastroscopy, yet it has a 2% chance of forming cancers. We report the case of a 52-year-old woman with solitary eGCT, then analysed retrospectivelyanalyze the clinical features and elucidate on the reduction of misdiagnosis and missed diagnosis.
A 52-year-old woman was diagnosed with "esophageal granulossoma" after esophagoscopy, which was mistaken for eGCT.
eGCT diagnosis depends on characteristic pathomorphologies and detection of the S-100 protein. Endoscopic mucosal resection is the preferred therapeutic method.
食管颗粒细胞瘤（eGCT）是一种相对罕见的、通常为良性的神经外胚层肿瘤。它起源于施万细胞。该疾病的临床症状不具有特异性。然而，最常见的症状是吞咽困难，在胃镜检查下大多被误诊为食管息肉，但它有2%的癌变几率。我们报告一例52岁患有孤立性eGCT的女性病例，然后回顾性分析其临床特征并阐明减少误诊和漏诊的方法。
一名52岁女性在食管镜检查后被诊断为“食管颗粒瘤”，该病例被误诊为eGCT。
eGCT的诊断依赖于特征性的病理形态学及S-100蛋白的检测。内镜下黏膜切除术是首选的治疗方法。
