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[接受胸主动脉腔内修复术治疗Stanford B型主动脉夹层患者的单纯肾囊肿与不良事件之间的关系]

[Relationship between simple renal cyst and adverse events in patients receiving thoracic endovascular aortic repair for Stanford B aortic dissection].

作者信息

Zhu Y, Luo S Y, Liu Y, Huang W H, He P C, Xie N J, Xue L, Luo J F

机构信息

Department of Cardiology, Vascular Center, Guangdong Provincial People's Hospital, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 2022 Aug 24;50(8):774-779. doi: 10.3760/cma.j.cn112148-20220430-00334.

Abstract

To explore the prognostic value of simple renal cyst (SRC) for adverse events in patients receiving thoracic endovascular aortic repair (TEVAR) for Stanford B aortic dissection (TBAD). This study is a retrospective cohort study. Consecutive patients receiving TEVAR for TBAD between January 2010 and December 2015 were enrolled in this study. The patients were divided into SRC group and non-SRC group. With sex and age ±2 years old as matching factors, SRC group and non-SRC group were matched by 1∶1. Collect and compare the differences of clinical data between the two groups. Adverse events were recorded through outpatient, telephone follow-up and in-hospital review. After adjusting for confounding factors, multivariate Cox regression was used to analyze the risk factors of aortic adverse events. Kaplan-Meier method was used to analyze the survival curve of SRC group and non-SRC group. A total of 692 consecutive patients were recruited. Patients were divided into SRC group (=235) and non-SRC group (=457). After 1∶1 matching, there were 229 cases in SRC group and no SRC group respectively. The age of SRC group was (62.3±10.4) years old, 209 cases were male (91.3%), and the age of no SRC group was (62.0±10.2) years old, 209 cases were male (91.3%). Cox regression analysis showed that, after adjusting for confounding factors, comorbid SRC (=1.991, 95%: 1.090-3.673, =0.025), TEVAR in the acute phase (=13.635, 95%: 5.969-31.147, =0.001), general anesthesia (=2.012, 95%: 1.066-3.799, =0.031) are independent factors of aortic-adverse events after TEVAR for TBAD. Kaplan-Meier analysis showed that the cumulative survival rate of SRC group was significantly lower than non-SRC group (log-rank =0.031, 0.005). SRC is an independent predictor of aortic-related adverse events in patients following TEVAR for TBAD.

摘要

探讨单纯性肾囊肿(SRC)对接受胸主动脉腔内修复术(TEVAR)治疗Stanford B型主动脉夹层(TBAD)患者不良事件的预后价值。本研究为回顾性队列研究。纳入2010年1月至2015年12月期间连续接受TEVAR治疗TBAD的患者。将患者分为SRC组和非SRC组。以性别和年龄±2岁作为匹配因素,SRC组和非SRC组按1∶1进行匹配。收集并比较两组临床资料的差异。通过门诊、电话随访及住院复查记录不良事件。校正混杂因素后,采用多因素Cox回归分析主动脉不良事件的危险因素。采用Kaplan-Meier法分析SRC组和非SRC组的生存曲线。共纳入692例连续患者。患者分为SRC组(=235例)和非SRC组(=457例)。1∶1匹配后,SRC组和非SRC组各有229例。SRC组年龄为(62.3±10.4)岁,男性209例(91.3%),非SRC组年龄为(62.0±10.2)岁,男性209例(91.3%)。Cox回归分析显示,校正混杂因素后,合并SRC(=1.991,95%可信区间:1.090 - 3.673,=0.025)、急性期行TEVAR(=13.635,95%可信区间:5.969 - 31.147,=0.001)、全身麻醉(=2.012,95%可信区间:1.066 - 3.799,=0.031)是TBAD患者TEVAR术后主动脉不良事件的独立因素。Kaplan-Meier分析显示,SRC组的累积生存率显著低于非SRC组(对数秩检验=0.031,=0.005)。SRC是TBAD患者TEVAR术后主动脉相关不良事件的独立预测因素。

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