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优质护理对糖尿病肾病血液透析患者的临床效果及其对炎症反应的影响

Clinical Effects of Primary Nursing on Diabetic Nephropathy Patients Undergoing Hemodialysis and Its Impact on the Inflammatory Responses.

作者信息

Guo Yujuan, Song Qi, Cui Yuhong, Wang Caihong

机构信息

Obstetrics Department, Chengyang District People's Hospital, Qingdao, Shandong, China.

Department of Blood Purification, The Third People's Hospital of Qingdao, Qingdao, Shandong, China.

出版信息

Evid Based Complement Alternat Med. 2022 Aug 9;2022:1011415. doi: 10.1155/2022/1011415. eCollection 2022.

DOI:10.1155/2022/1011415
PMID:35983002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9381212/
Abstract

OBJECTIVE

To assess the clinical effects of primary nursing on diabetic nephropathy patients undergoing hemodialysis and its impact on inflammatory responses.

METHODS

Between July 2019 and April 2021, 80 patients with diabetic nephropathy who underwent hemodialysis in our institution were recruited and assigned at a ratio of 1 : 1 to receive either routine nursing (routine group) or primary nursing (primary group). The outcome measures included nursing outcomes, inflammatory factor levels, and psychological status.

RESULTS

Primary nursing resulted in lower levels of blood creatinine, fasting glucose, urea nitrogen, and proteinuria versus routine nursing ( < 0.05). Patients receiving primary nursing showed significantly lower levels of interleukin (IL)-6, high-sensitivity C-reactive protein (hs-CRP), and tumor necrosis factor-alpha (TNF-) versus those given routine nursing ( < 0.05). The patients in the primary group had significantly lower scores on the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) versus those in the routine group ( < 0.05).

CONCLUSION

Primary nursing improves the renal function of diabetic nephropathy patients undergoing hemodialysis, reduces the inflammatory response, and eliminates their negative emotions, which shows great potential for clinical application.

摘要

目的

评估责任制护理对接受血液透析的糖尿病肾病患者的临床效果及其对炎症反应的影响。

方法

2019年7月至2021年4月,选取在我院接受血液透析的80例糖尿病肾病患者,按1∶1比例分为两组,分别接受常规护理(常规组)和责任制护理(责任制组)。观察指标包括护理效果、炎症因子水平及心理状态。

结果

与常规护理相比,责任制护理可降低患者血肌酐、空腹血糖、尿素氮及蛋白尿水平(P<0.05)。与常规护理相比,接受责任制护理的患者白细胞介素(IL)-6、高敏C反应蛋白(hs-CRP)及肿瘤坏死因子-α(TNF-α)水平显著降低(P<0.05)。责任制组患者的焦虑自评量表(SAS)和抑郁自评量表(SDS)评分显著低于常规组(P<0.05)。

结论

责任制护理可改善接受血液透析的糖尿病肾病患者的肾功能,减轻炎症反应,消除负面情绪,具有较大的临床应用潜力。

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Retracted: Clinical Effects of Primary Nursing on Diabetic Nephropathy Patients Undergoing Hemodialysis and Its Impact on the Inflammatory Responses.撤回:责任制护理对血液透析糖尿病肾病患者的临床效果及其对炎症反应的影响
Evid Based Complement Alternat Med. 2023 Jul 19;2023:9863031. doi: 10.1155/2023/9863031. eCollection 2023.

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Comput Math Methods Med. 2021 Dec 22;2021:3665460. doi: 10.1155/2021/3665460. eCollection 2021.
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GSDMD-mediated pyroptosis: a critical mechanism of diabetic nephropathy.GSDMD 介导的细胞焦亡:糖尿病肾病的关键机制。
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Early detection of diabetic nephropathy in patient with type 2 diabetes mellitus: A review of the literature.早期检测 2 型糖尿病患者的糖尿病肾病:文献综述。
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