Kanazawa Hironobu
Department of Palliative Care Medicine, Sagara Hospital, Kagoshima, Japan.
Palliat Med Rep. 2021 Dec 9;2(1):348-354. doi: 10.1089/pmr.2021.0052. eCollection 2021.
Femoral pathological fractures (PFs) due to bone metastasis result in exacerbation of pain, gait disturbance, and reduced general condition. Surgery may be considered depending on the situation, but is not suggested often, and treatment is difficult toward the end of life.
Terminal cancer patients with a femoral PF admitted to a palliative care unit (PCU) were retrospectively evaluated.
Seven cancer patients diagnosed with a femoral PF at a PCU on admission, in Japan, were examined for clinical background, physical symptoms, and psychiatric symptoms. In addition, the responses of the patients' families and medical staff were examined. This study was approved by the ethics board of our hospital.
A total of 28.6% of patients were hospitalized from home, and the trigger for PF could not be confirmed in 85.7% of patients. In all cases, surgery was not recommended, given the poor prognosis. Opioid drugs were used for pain in all patients, and 85.7% of patients were able to relieve their symptoms. Delirium was observed in 71.4% of cases, and treatment with antipsychotics was required in all cases. Family grief also emerged as a problem, and the staff was burdened; hence, we addressed this at the death conference.
Even for femoral PFs in cancer patients with a limited prognosis, it is necessary to perform tests and control pain. In addition, it is important to support the mental distress of patients and their families in a short period; medical staff should be trained to support the families after the patients' death.
骨转移导致的股骨病理性骨折(PFs)会加剧疼痛、步态障碍并使全身状况恶化。可根据具体情况考虑手术,但并不常建议进行,且在生命末期治疗困难。
对入住姑息治疗病房(PCU)的股骨PFs终末期癌症患者进行回顾性评估。
对日本一家PCU收治的7例入院时被诊断为股骨PFs的癌症患者的临床背景、身体症状和精神症状进行了检查。此外,还对患者家属和医护人员的反应进行了调查。本研究经我院伦理委员会批准。
共有28.6%的患者从家中入院,85.7%的患者无法确定PFs的触发因素。鉴于预后较差,所有病例均不建议手术。所有患者均使用阿片类药物止痛,85.7%的患者症状得到缓解。71.4%的病例出现谵妄,所有病例均需要使用抗精神病药物治疗。家属的悲痛也成为一个问题,医护人员负担沉重;因此,我们在死亡讨论会上解决了这个问题。
即使对于预后有限的癌症患者的股骨PFs,也有必要进行检查并控制疼痛。此外,在短时间内支持患者及其家属的精神痛苦很重要;应对医护人员进行培训,以便在患者去世后为家属提供支持。