Institute of Biomedicine (IBIOMED), University of León, León, Spain.
Getafe University Hospital.
Medicine (Baltimore). 2022 Aug 19;101(33):e29954. doi: 10.1097/MD.0000000000029954.
This observational, cross-sectional case-control study evaluates the impact of coronavirus disease 2019 (COVID-19) on health-related quality of life (HRQoL) in elderly persons who have undergone surgery for adult spinal deformity (ASD). On December 31, 2019, the Chinese authorities first reported severe acute respiratory syndrome coronavirus 2, and on March 11, 2020, it was declared a pandemic. The pandemic seems to have had a negative effect on elderly patients who underwent ASD, in terms of functional and psychological quality of life. We selected patients with ASD aged > 70 years who had undergone surgery between 2010 and 2015 and compared them with age- and sex-matched patients who did not have ASD. We recorded sociodemographic variables, type of surgery, levels of spinal fusion, HRQoL (Scoliosis Research Society-22, Short Form 12 Health Survey, EuroQol-5D [EQ-5], Geriatric Depression Scale [Yesavage] [GDS], Modified Frailty Index-11, and Barthel index), fear of visiting a health center, fear of leaving one's house, and adherence to preventive measures. The study population comprised 174 patients (mean [standard deviation] age, 77.3 [5.9] years; 86% women), of whom 87 had undergone surgery for ASD. The incidence of COVID-19 was higher in patients aged > 85 years (P = .041), urban areas (P = .047), and in patients in long-term care (P = .03). Similarly, no differences were observed for the ability to cope with the pandemic (P > .05). Patients who underwent surgery also had a higher risk of depression (GDS, 6.7 [P = .02]), a lower EQ-5 score (P = .001), a higher body mass index (P = .004), greater consumption of drugs (P < .001), especially opiates (P < .001). Patients who underwent surgery constitute a vulnerable population during the COVID-19 pandemic, with poorer quality of life and had a much higher risk of depression. They are also polymedicated and prefrail, adhere well to COVID-19 preventive measures, and do not seem to fear visiting health centers.
这项观察性、横断面病例对照研究评估了 2019 年冠状病毒病（COVID-19）对接受成人脊柱畸形（ASD）手术的老年患者健康相关生活质量（HRQoL）的影响。2019 年 12 月 31 日，中国当局首次报告严重急性呼吸综合征冠状病毒 2 型，2020 年 3 月 11 日，该病毒被宣布为大流行。大流行似乎对接受 ASD 手术的老年患者的功能和心理生活质量产生了负面影响。我们选择了 2010 年至 2015 年间接受手术的年龄>70 岁的 ASD 患者，并将其与年龄和性别匹配的无 ASD 患者进行了比较。我们记录了社会人口统计学变量、手术类型、脊柱融合水平、HRQoL（脊柱侧凸研究协会 22 项、健康调查 12 项简表、欧洲五维健康量表[EQ-5]、老年抑郁量表[Yesavage][GDS]、改良衰弱指数 11 项和巴氏指数）、害怕去医疗机构就诊、害怕离家、以及对预防措施的依从性。研究人群包括 174 名患者（平均[标准差]年龄为 77.3[5.9]岁；86%为女性），其中 87 名患者接受了 ASD 手术。85 岁以上患者（P=0.041）、城市地区（P=0.047）和长期护理患者（P=0.03）COVID-19 发病率较高。同样，在应对大流行的能力方面，两组之间也没有差异（P>0.05）。接受手术的患者也有更高的抑郁风险（GDS，6.7[P=0.02]）、EQ-5 评分较低（P=0.001）、体重指数较高（P=0.004）、药物消费更高（P<0.001），特别是阿片类药物（P<0.001）。COVID-19 大流行期间，接受手术的患者构成一个脆弱人群，生活质量较差，抑郁风险更高。他们还同时服用多种药物，身体虚弱，对 COVID-19 预防措施依从性良好，似乎并不害怕去医疗机构就诊。
