Cocores J A, Patel M D, Gold M S, Pottash A C
J Nerv Ment Dis. 1987 Jul;175(7):431-2. doi: 10.1097/00005053-198707000-00007.
Cocaine is a potent dopamine agonist that frequently stimulates the central nervous system and is often manifested by increased psychomotor activity, impulsivity, euphoria, and rapid thoughts. Attention deficit disorder (ADD) and bipolar disorder also present with physical restlessness, racing thoughts, distractibility, and mood instability. Although these three disorders rarely appear in the same individual, they are important differential diagnoses when considering any one illness with the above symptom complexes. We report two cases of cocaine abuse with ADD residual type in patients who were previously diagnosed as having atypical bipolar disorder. The adverse effects were reversed by the dopamine agonist bromocriptine.
可卡因是一种强效多巴胺激动剂，常刺激中枢神经系统，常表现为精神运动活动增加、冲动、欣快感和思维奔逸。注意力缺陷障碍（ADD）和双相情感障碍也表现为身体躁动、思维奔逸、注意力分散和情绪不稳定。虽然这三种疾病很少出现在同一个体中，但在考虑任何一种具有上述症状复合体的疾病时，它们都是重要的鉴别诊断。我们报告了2例先前被诊断为非典型双相情感障碍的患者出现ADD残留型可卡因滥用的病例。多巴胺激动剂溴隐亭逆转了这些不良反应。
