Department of Conservative Dentistry, Faculty of Dentistry, Cairo University, Cairo, Egypt; Conservative and Esthetic Dentistry Department, Faculty of Dentistry, Modern University for Technology and Information, Cairo, Egypt, Phone: +20 1016524841, e-mail:
Department of Conservative Dentistry, Faculty of Dentistry, Cairo University, Cairo, Egypt.
J Contemp Dent Pract. 2022 May 1;23(5):520-526.
This study was conducted to evaluate the remineralization potential of Remin Pro Forte vs Remin Pro remineralizing agents on white spot lesions (WSLs) post-orthodontic treatment.
Twenty patients with post-orthodontic WSLs were divided into the following two equal groups based on treatment ( = 10): (1) A 3-month program of hydroxyapatite, fluoride, xylitol, ginger, curcuma-containing cream (Remin Pro Forte) as intervention group; (2) A 3-month cream regimen including hydroxyapatite and fluoride, xylitol (Remin Pro) as control group. The main outcomes including caries regression (assessed by ICDAS II), mineral content (assessed by VistaCam iX camera), and color of WSLs (assessed by digital image analysis by Adobe photoshop) were measured at the time of enrollment and 1, 2, and 3 months afterward. Mann-Whitney test used to compare between tested groups. The statistical significance was set at <0.05.
Both Remin Pro Forte and Remin Pro elicited much better caries regression and significantly higher mineral content in WSLs over a 3-month period ( <0.05). However, the difference in mineral content of WSLs between groups did not reach statistical significance ( = 0.414). In both experimental groups, the appearance of WSLs improved significantly ( <0.05).
Both Remin Pro Forte and Remin Pro were successful in reducing caries, increasing mineral content, and enhancing the appearance of demineralized enamel, indicating that both products could be suggested for post-orthodontic WSL management.
Natural herbal products could be employed as remineralizing agents and included into tooth preventive measures. It is a less harmful alternative to traditional chemical remineralization methods.
本研究旨在评估 Remin Pro Forte 与 Remin Pro 再矿化剂在正畸治疗后白斑（WSL）再矿化的潜力。
将 20 名正畸后 WSL 患者分为以下两组（每组 n = 10）：（1）羟基磷灰石、氟化物、木糖醇、生姜、含姜黄素的乳膏（Remin Pro Forte）治疗 3 个月为干预组；（2）羟基磷灰石和氟化物、木糖醇乳膏治疗 3 个月为对照组。主要结局包括龋齿消退（ICDAS II 评估）、矿物质含量（VistaCam iX 相机评估）和 WSL 颜色（Adobe photoshop 数字图像分析评估），在入组时以及 1、2 和 3 个月后进行测量。采用 Mann-Whitney 检验比较两组间的差异。统计学意义设定为 <0.05。
Remin Pro Forte 和 Remin Pro 在 3 个月内均能显著改善龋齿消退和 WSL 中矿物质含量（ <0.05）。然而，两组 WSL 矿物质含量差异无统计学意义（ = 0.414）。在两个实验组中，WSL 的外观均有显著改善（ <0.05）。
Remin Pro Forte 和 Remin Pro 均能成功减少龋齿、增加矿物质含量、改善脱矿釉质的外观，表明这两种产品均可用于正畸后 WSL 管理。
天然草药产品可作为再矿化剂，并纳入牙齿预防措施。这是一种比传统化学再矿化方法危害更小的替代方法。
