Wach Michael M, Myneni Ajay A, Miller Lorin, Boccardo Joseph, Ibrahim-Zada Irada, Schwaitzberg Steven S, Noyes Katia, Gajdos Csaba
Department of Surgery, University at Buffalo, Buffalo, New York, USA.
Department of Epidemiology and Environmental Health, Division of Health Services Policy and Practice, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA.
J Surg Oncol. 2022 Dec;126(8):1434-1441. doi: 10.1002/jso.27075. Epub 2022 Aug 20.
Minimally invasive techniques for pancreaticoduodenectomy (PD) are increasing in practice, however, data remains limited regarding perioperative outcomes. Our study sought to compare patients undergoing open pancreaticoduodenectomy (OPD) with those undergoing laparoscopic (LPD) or robot-assisted pancreaticoduodenectomy (RPD).
Patients who underwent PD during 2016-2018 were identified from the New York State Planning and Research Cooperative System database.
Of the 1954 patients identified, 1708 (87.4%) underwent OPD, 165 (8.4%) underwent LPD, and 81 (4.2%) underwent RPD. The majority of patients were White (63.8%), males (53.3%) with a mean age of 65.4 years. RPD patients had a lower median Charlson Comorbidity Index (2) than OPD (3) or LPD (3, p = 0.01) and had a lower 30-day rate of complications (35.8% vs. 48.3% vs. 43.6% respectively, p = 0.05). After propensity-score matching, however, there were no differences between the groups regarding overall complications, surgical site infections, anastomotic leaks, or mortality (p = NS for all). OPD demonstrated a longer length of stay (median 8 days) compared to LPD (7 days) or RPD (7 days, p < 0.01).
Patients undergoing LPD and RPD have a shorter length of hospital stay compared to OPD and there was no difference in overall morbidity or mortality when matched to similar patients.
胰十二指肠切除术(PD)的微创技术在实践中日益增多,然而,关于围手术期结果的数据仍然有限。我们的研究旨在比较接受开放胰十二指肠切除术(OPD)的患者与接受腹腔镜(LPD)或机器人辅助胰十二指肠切除术(RPD)的患者。
从纽约州规划与研究合作系统数据库中识别出2016 - 2018年期间接受PD的患者。
在1954例被识别的患者中,1708例(87.4%)接受了OPD,165例(8.4%)接受了LPD,81例(4.2%)接受了RPD。大多数患者为白人(63.8%),男性(53.3%),平均年龄65.4岁。RPD患者的Charlson合并症指数中位数(2)低于OPD(3)或LPD(3,p = 0.01),且30天并发症发生率较低(分别为35.8%、48.3%和43.6%,p = 0.05)。然而,在倾向评分匹配后,各组在总体并发症、手术部位感染、吻合口漏或死亡率方面没有差异(所有p值均无统计学意义)。与LPD(7天)或RPD(7天)相比,OPD的住院时间更长(中位数8天,p < 0.01)。
与OPD相比,接受LPD和RPD的患者住院时间更短,与相似患者匹配时,总体发病率或死亡率没有差异。