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抑郁症患者的下尿路症状和性功能。

Lower urinary tract symptoms and sexual functioning in patients with depression.

机构信息

Uniwersytet Jagielloński Collegium Medicum, Wydział Lekarski, Oddział Kliniczny Urologii.

Uniwersytet Jagielloński Collegium Medicum, Wydział Lekarski, Oddział Kliniczny Psychiatrii Dorosłych.

出版信息

Psychiatr Pol. 2022 Apr 30;56(2):309-321. doi: 10.12740/PP/OnlineFirst/131532.

Abstract

OBJECTIVES

A link between sexual functioning and depression has been reported. However, it is still unknown whether lower urinary tract symptoms (LUTS) coexist or correlate with sexual dysfunction (SD) in depressed individuals. Depressed patients represent a unique population because of a possible bidirectional relationship between SD and depression and between LUTS and depression. Thus, the aim of this study was to investigate relationships between depression severity, SD and LUTS for patients with depression.

METHODS

In this cross-sectional study, we analyzed data on depression, sexual functioning and LUTS from depressed patients who were treated in our department of adult psychiatry. Data were obtained from the Hamilton Rating Scale for Depression, the International Index of Erectile Function (IIEF), the Female Sexual Function Index (FSFI), and the International Prostate Symptom Score (IPSS).

RESULTS

We included one hundred two patients diagnosed with, and treated for, depression. The participants reported a high overall prevalence of SD (60.8%), and SD correlated with depression severity. LUTS were also highly prevalent with 86% of the participants reporting at least mild LUTS severity. Despite coexistence of LUTS and SD in multiple patients, we did not find a statistically significant relationship between LUTS and SD in our cohort.

CONCLUSIONS

In our exclusive group of individuals diagnosed with, and treated for, depression, depression severity had a negative effect on sexual functioning. Although there was no statistically significant relationship between LUTS and SD, they coexisted in multiple patients. Therefore, LUTS and SD should still be systematically assessed in patients with depression.

摘要

目的

已有研究报道性功能与抑郁之间存在关联。然而,在抑郁个体中,下尿路症状(LUTS)是否与性功能障碍(SD)共存或相关仍不清楚。抑郁患者是一个独特的群体,因为 SD 和抑郁之间以及 LUTS 和抑郁之间可能存在双向关系。因此,本研究旨在探讨抑郁患者的抑郁严重程度、SD 和 LUTS 之间的关系。

方法

在这项横断面研究中,我们分析了在我院成人精神病科接受治疗的抑郁患者的抑郁、性功能和 LUTS 数据。数据来自汉密尔顿抑郁评定量表、国际勃起功能指数(IIEF)、女性性功能指数(FSFI)和国际前列腺症状评分(IPSS)。

结果

我们纳入了 102 名被诊断为并接受抑郁治疗的患者。参与者报告 SD 的总体患病率较高(60.8%),SD 与抑郁严重程度相关。LUTS 的患病率也很高,86%的参与者报告至少存在轻度 LUTS 严重程度。尽管在多名患者中存在 LUTS 和 SD 共存,但我们在本队列中未发现 LUTS 和 SD 之间存在统计学显著关系。

结论

在我们专门诊断和治疗抑郁的人群中,抑郁严重程度对性功能有负面影响。尽管 LUTS 和 SD 之间没有统计学显著关系,但它们在多名患者中同时存在。因此,在抑郁患者中仍应系统评估 LUTS 和 SD。

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