Skalski Michał, Przydacz Mikolaj, Sobański Jerzy A, Cyranka Katarzyna, Klasa Katarzyna, Datka Wojciech, Gołąbek Tomasz, Chłosta Piotr, Dudek Dominika
Uniwersytet Jagielloński Collegium Medicum, Katedra Psychiatrii, Klinika Psychiatrii Dorosłych.
Uniwersytet Jagielloński Collegium Medicum, Oddział Kliniczny Urologii.
Psychiatr Pol. 2019 Aug 31;53(4):939-953. doi: 10.12740/PP/OnlineFirst/94704.
The aim of the present study was to investigate the correlation between lower urinary tract symptoms (LUTS) and severity of depressive symptoms in patients treated for depression.
102 patients (43 males, 59 females) aged 20-67 (M = 46.1) treated for depression were included in this cross-sectional analysis. Depressive symptoms were assessed with the 17-item Hamilton Depression Rating Scale (HDRS) and Quick Inventory of Depressive Symptomatology - Self Report (QIDS-SR). LUTS were examined with the International Prostate Symptom Score (IPSS). In order to analyze the impact of presented symptoms, both urological and psychiatric, on quality of life of analyzed individuals the 30-item General Health Questionnaire (GHQ-30) was used.
The average IPSS score in women was significantly higher than in men (9.59 vs. 6; p = 0.04). Patients suffering from at least moderate depression assessed with QIDS-SR had significantly higher scores in IPSS (9.76 vs. 4.1; p = 0.002). Severity of all LUTS assessed with IPSS correlated with QIDS-SR score in examined men (p < 0.05). In women, the total IPSS score correlated with the QIDS-SR score (p < 0.05) and with the total GHQ-30 score (p < 0.05). Anumber of other significant (p < 0.05) correlations were observed between the total IPSS score and certain items' scores in the GHQ-30 both in men and women.
LUTS are common among patients with depression. There is a correlation between severity of depressive symptoms and LUTS. LUTS affect quality of life and well-being as well as cause marked distress in depressed patients. Comorbidity of LUTS and depression should draw attention of both psychiatrists and urologists and enhance interdisciplinary treatment approach. Further prospective and cohort studies are essential to reveal more details of the correlation between LUTS and depression.
本研究旨在调查抑郁症患者下尿路症状（LUTS）与抑郁症状严重程度之间的相关性。
本横断面分析纳入了102例年龄在20 - 67岁（平均年龄46.1岁）的抑郁症患者（43例男性，59例女性）。采用17项汉密尔顿抑郁量表（HDRS）和抑郁症状快速自评量表（QIDS - SR）评估抑郁症状。使用国际前列腺症状评分（IPSS）检查LUTS。为了分析所呈现的泌尿系统和精神系统症状对被分析个体生活质量的影响，采用了30项一般健康问卷（GHQ - 30）。
女性的平均IPSS评分显著高于男性（9.59对6；p = 0.04）。用QIDS - SR评估为至少中度抑郁的患者，其IPSS评分显著更高（9.76对4.1；p = 0.002）。在接受检查的男性中，用IPSS评估的所有LUTS严重程度与QIDS - SR评分相关（p < 0.05）。在女性中，IPSS总分与QIDS - SR评分相关（p < 0.05），且与GHQ - 30总分相关（p < 0.05）。在男性和女性中，IPSS总分与GHQ - 30中某些项目的评分之间还观察到许多其他显著（p < 0.05）的相关性。
LUTS在抑郁症患者中很常见。抑郁症状的严重程度与LUTS之间存在相关性。LUTS影响生活质量和幸福感，也给抑郁症患者带来明显困扰。LUTS与抑郁症的共病情况应引起精神科医生和泌尿科医生的关注，并加强跨学科治疗方法。进一步的前瞻性和队列研究对于揭示LUTS与抑郁症之间相关性的更多细节至关重要。
