Areniello Marica, Matassa Silvio, Esposito Giovanni, Lens Piet N L
National University of Ireland Galway, University Road, Galway, H91 TK33, Ireland.
Department of Civil, Architectural and Environmental Engineering, University of Naples Federico II, Naples, 80125, Italy.
Trends Biotechnol. 2023 Feb;41(2):197-213. doi: 10.1016/j.tibtech.2022.07.008. Epub 2022 Aug 19.
Securing a sustainable protein supply at the global level is among the greatest challenges currently faced by humanity. Alternative protein sources, such as second-generation microbial protein (MP), could give rise to innovative circular bioeconomy practices, synthesizing high-value bioproducts through the recovery and upcycling of resources from overabundant biowastes and residues. Within such a multi-feedstock biorefinery scenario, the wide range of microbial pathways and networks that characterize mixed microbial cultures, offers interesting and not yet fully explored advantages over conventional monoculture-based processes. In this review, we combine a comprehensive analysis of waste recovery platforms for second-generation MP production with a critical evaluation of the research gaps and potentials offered by mixed culture-based MP fermentation processes.
在全球层面确保可持续的蛋白质供应是人类目前面临的最大挑战之一。替代性蛋白质来源，如第二代微生物蛋白（MP），可能催生创新的循环生物经济实践，通过从过剩的生物废弃物和残渣中回收资源并进行升级再造来合成高价值生物产品。在这样一个多原料生物精炼场景中，混合微生物培养所特有的广泛微生物途径和网络，相较于传统的基于单一培养的工艺具有一些有趣且尚未得到充分探索的优势。在本综述中，我们将对用于第二代MP生产的废物回收平台进行全面分析，同时对基于混合培养的MP发酵工艺所存在的研究差距和潜力进行批判性评估。
