Sehgal Vineet, Bansal Priyanshu, Arora Shaifali, Kapila Saniya, Bedi Gaganpreet S
Neurology, Amandeep Medicity, Amritsar, IND.
Neurology, Sehgal's Neuro and Child Care Centre, Amritsar, IND.
Cureus. 2022 Jul 19;14(7):e27024. doi: 10.7759/cureus.27024. eCollection 2022 Jul.
A variety of neurological complications of COVID-19 vaccinations are reported with each passing day. We report a rare case of a patient who developed brain stem and spinal cord lesions 20 days after the first dose of the ChAdOx1 nCoV-19 coronavirus vaccine. On further investigation, anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies were strongly positive, and a diagnosis of myelin oligodendrocyte glycoprotein antibody disease (MOGAD) was made. This case report aims to add a rare entity to the possible complications of COVID-19 vaccines and discuss symptoms, MRI findings, and the differential diagnosis of MOGAD. We also suggest that these patients undergo follow-up serological tests to recognize recurrences quickly.
随着时间的推移，每天都有关于新冠疫苗各种神经系统并发症的报道。我们报告了一例罕见病例，一名患者在接种第一剂ChAdOx1 nCoV-19冠状病毒疫苗20天后出现脑干和脊髓病变。进一步检查发现，抗髓鞘少突胶质细胞糖蛋白（anti-MOG）抗体呈强阳性，确诊为髓鞘少突胶质细胞糖蛋白抗体病（MOGAD）。本病例报告旨在为新冠疫苗可能的并发症增添一种罕见情况，并讨论MOGAD的症状、磁共振成像（MRI）表现及鉴别诊断。我们还建议对这些患者进行随访血清学检测，以便快速识别复发情况。
