Sun Jing, Wang Sheng, Chen Biquan
Department of Infectious Diseases, Anhui Provincial Children's Hospital, Hefei, China.
Front Pediatr. 2022 Aug 4;10:903285. doi: 10.3389/fped.2022.903285. eCollection 2022.
Caroli's disease is a rare congenital bile duct malformation characterized by intrahepatic bile duct dilatation. This kind of situation is seldom encountered in clinical work. We report such a case who presented to our emergency department with recurrent fever as initial symptom. According to the clinical manifestation and imaging examination, a 13-year-old boy was diagnosed with suppurative cholangitis and sepsis caused by Caroli's disease. The symptoms were got relieved after antibiotic therapy upgraded from cephalosporins to carbapenems. After 5 months of follow-up, he did not have fever, abdominal pain or any other discomfort. We believe the present report is of medical significance since it serves as a reminder that Caroli's disease may have atypical presentations and be masked by non-specific clinical findings. The report hopes to enlighten our pediatric colleagues by providing more knowledge on such rare congenital disease.
卡罗里病是一种罕见的先天性胆管畸形，其特征为肝内胆管扩张。这种情况在临床工作中很少遇到。我们报告这样一例，该患者以反复发热为首发症状就诊于我院急诊科。根据临床表现和影像学检查，一名13岁男孩被诊断为卡罗里病引起的化脓性胆管炎和脓毒症。在抗生素治疗从头孢菌素升级为碳青霉烯类后症状缓解。经过5个月的随访，他没有发热、腹痛或任何其他不适。我们认为本报告具有医学意义，因为它提醒人们卡罗里病可能有非典型表现，并被非特异性临床发现所掩盖。本报告希望通过提供更多关于这种罕见先天性疾病的知识，启发我们的儿科同事。
