Xing Lihua, Haddao Kadhim Madjeed, Emami Nafiseh, Nalchifard Fereshteh, Hussain Woorod, Jasem Hadeer, Dawood Ashour H, Toghraie Davood, Hekmatifar Maboud
School of Resources, Environment and Architectural Engineering, Chifeng University, Chifeng, Inner Mongolia, 024000, China.
Biomedical Engineering Department, University of Kerbala, Iraq.
Sustain Chem Pharm. 2022 Oct;29:100757. doi: 10.1016/j.scp.2022.100757. Epub 2022 Jun 21.
Doxycycline and Naproxen are among the most widely used drugs in the therapy of CoVID 19 disease found in surface water. Water scarcity in recent years has led to research to treat polluted water. One of the easy and low-cost methods for treatment is adsorption. The utilize of Metal-Organic Frameworks (MOFs) to evacuate pharmaceutical contaminants from water sources has been considered by researchers in the last decade. In this research, HKUST-1/ZnO/SA composite with high adsorption capacity, chemical and water stability, recovery, and reuse properties has been synthesized and investigated. By adding 10 wt% of ZnO and 50 wt% of sodium alginate to HKUST-1, at 25 °C and pH = 7, the specific surface area is reduced by 60%. The parameters of drugs concentration C =(5,80) mg/L, time=(15,240) min, and pH= (2,12) were investigated, and the results showed that the HKUST-1/ZnO/SA is stable in water for 14 days and it can be used in 10 cycles with 80% removal efficiency. The maximum Adsorption loading of doxycycline and Naproxen upon HKUST-1/ZnO/SA is 97.58 and 80.04 mg/g, respectively. Based on the correlation coefficient (R), the pseudo-second-order and the Langmuir isotherm models were selected for drug adsorption. The proposed mechanism of drug uptake is by MOFs, hydrogen bonding, electrostatic bonding, and acid-base interaction.
强力霉素和萘普生是地表水中发现的用于治疗新冠病毒疾病的最广泛使用的药物之一。近年来的水资源短缺促使人们开展处理受污染水的研究。吸附是一种简便且低成本的处理方法。在过去十年中，研究人员已考虑利用金属有机框架（MOFs）从水源中去除药物污染物。在本研究中，已合成并研究了具有高吸附容量、化学和水稳定性、可回收及可重复使用特性的HKUST-1/ZnO/SA复合材料。通过在HKUST-1中添加10 wt%的ZnO和50 wt%的海藻酸钠，在25°C和pH = 7的条件下，比表面积降低了60%。研究了药物浓度C =(5,80) mg/L、时间=(15,240) min和pH = (2,12)等参数，结果表明HKUST-1/ZnO/SA在水中稳定14天，并且可以在10个循环中使用，去除效率达80%。HKUST-1/ZnO/SA对强力霉素和萘普生的最大吸附量分别为97.58和80.04 mg/g。基于相关系数（R），选择了伪二级和朗缪尔等温线模型用于药物吸附。提出的药物吸附机制是通过MOFs、氢键、静电键和酸碱相互作用。
