Amirian Mahtab, Ghorbani-Vaghei Ramin, Alavinia Sedigheh
Department of Organic Chemistry, Faculty of Chemistry and Petroleum Sciences, Bu-Ali Sina University 6517838683 Hamadan Iran
Department of Organic Chemistry, Faculty of Chemistry, University of Guilan Rasht Iran.
Nanoscale Adv. 2025 Jul 21. doi: 10.1039/d5na00299k.
This research introduces a recyclable and environmentally friendly catalyst, Co(BDC-NH)-TA-PY, for the efficient synthesis of triazoles the reaction of benzaldehydes, nitromethane, and sodium azide. The synthesis of Co(BDC-NH)-TA-PY was carried out through the post-synthetic modification of Co(BDC-NH), incorporating triazine-pyrimidine (TA-PY) functional groups. The key advantage of this catalyst lies in its dual functionality: the Lewis acidic sites of the Co(BDC-NH) metal-organic framework (MOF) are complemented by the Brønsted basic sites of the triazine and pyrimidine groups. This study represents the first example of a post-synthetic modification of the Co(BDC-NH) metal-organic framework (MOF) by integrating triazine and pyrimidine functional groups, which significantly enhanced its catalytic performance. The abundant TA-PY ligand increased the catalytic activity from 42% to 94%. Co(BDC-NH) nanocrystals were successfully synthesized and characterized, exhibiting a highly crystalline structure. Following the post-synthetic modification to synthesize Co(BDC-NH)-TA-PY, the catalyst retained its uniform morphology, ensuring consistent structural integrity. Furthermore, the structural integrity, morphology, and chemical composition of the reused Co(BDC-NH)-TA-PY were thoroughly examined, revealing no significant differences between the fresh and reused catalysts. These results highlight the potential of functionalized cobalt-based metal-organic frameworks as versatile and sustainable catalysts for broader organic reactions.
本研究引入了一种可回收且环保的催化剂Co(BDC-NH)-TA-PY，用于通过苯甲醛、硝基甲烷和叠氮化钠的反应高效合成三唑。Co(BDC-NH)-TA-PY的合成是通过对Co(BDC-NH)进行后合成修饰来实现的，引入了三嗪-嘧啶(TA-PY)官能团。这种催化剂的关键优势在于其双重功能：Co(BDC-NH)金属有机框架(MOF)的路易斯酸性位点与三嗪和嘧啶基团的布朗斯特碱性位点相互补充。本研究是通过整合三嗪和嘧啶官能团对Co(BDC-NH)金属有机框架(MOF)进行后合成修饰的首个实例，这显著提高了其催化性能。丰富的TA-PY配体将催化活性从42%提高到了94%。成功合成并表征了Co(BDC-NH)纳米晶体，其呈现出高度结晶的结构。在进行后合成修饰以合成Co(BDC-NH)-TA-PY后，催化剂保持了其均匀的形态，确保了结构完整性的一致性。此外，对重复使用的Co(BDC-NH)-TA-PY的结构完整性、形态和化学成分进行了全面检查，结果表明新鲜催化剂和重复使用的催化剂之间没有显著差异。这些结果突出了功能化钴基金属有机框架作为通用且可持续的催化剂用于更广泛有机反应的潜力。
