Liao Jingwen, Chen Yanyu, Cai Li, Wang Kun, Wu Shenghui, Wu Lan, Song Bixiao, Hu Min, Hou Xiaohui
Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion, Guangzhou Sport University, Guangzhou, China.
Scientific Research Center, Guangzhou Sport University, Guangzhou, China.
Front Oncol. 2022 Aug 5;12:807531. doi: 10.3389/fonc.2022.807531. eCollection 2022.
The aim of the current study is to investigate the impact of Baduanjin, a traditional Chinese exercise, on quality of life and sleep quality in breast cancer survivors receiving aromatase inhibitor (AI) therapy.
A total of 72 breast cancer survivors who had received AI treatment for more3 than 6 months were enrolled in the current study using non-probability consecutive sampling procedure. Participants were randomly assigned in a 1:1 ratio to a 12-week Baduanjin exercise program or to a wait-list control group. The Baduanjin exercise group performed two 90-min supervised sessions per week. The primary outcomes were changes in quality of life measured by the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 (EORTC QLQ-C30) and in sleep quality evaluated using the Pittsburgh Sleep Quality Index (PSQI).
A total of 68 participants completed the trial (Baduanjin exercise group: n = 33; control group: n = 35). Baseline values for quality of life did not differ between groups. Both global quality of life and physical functioning scores increased significantly by 12.39 (P < 0.001) and 8.48 (P < 0.001) in the Baduanjin exercise group compared with those in the control. Overall PSQI score also decreased by 4.85 (P < 0.001) in the Baduanjin exercise group, whereas it increased by 0.34 in the control group.
Baduanjin exercise training led to improvement in the quality of life and sleep quality of breast cancer patients undergoing AI therapy.
本研究旨在探讨中国传统运动八段锦对接受芳香化酶抑制剂(AI)治疗的乳腺癌幸存者生活质量和睡眠质量的影响。
采用非概率连续抽样程序,共纳入72名接受AI治疗超过6个月的乳腺癌幸存者。参与者按1:1比例随机分为12周八段锦运动计划组或等待名单对照组。八段锦运动组每周进行两次90分钟的有监督训练。主要结局指标为通过欧洲癌症研究与治疗组织生活质量问卷核心30(EORTC QLQ-C30)测量的生活质量变化,以及使用匹兹堡睡眠质量指数(PSQI)评估的睡眠质量变化。
共有68名参与者完成试验(八段锦运动组:n = 33;对照组:n = 35)。两组生活质量的基线值无差异。与对照组相比,八段锦运动组的总体生活质量和身体功能评分分别显著提高了12.39(P < 0.001)和8.48(P < 0.001)。八段锦运动组的PSQI总分也下降了4.85(P < 0.001),而对照组则上升了0.34。
八段锦运动训练可改善接受AI治疗的乳腺癌患者的生活质量和睡眠质量。