Chuang Chia-Wen, Tsai Ming-Yen, Wu Shih-Chung, Liao Wen-Chun
Department of Nursing, Kaohsiung Chang Gung Memorial Hospital, Taiwan.
Department of Public Health, China Medical University, Taichung, Taiwan.
Integr Cancer Ther. 2024 Jan-Dec;23:15347354241308857. doi: 10.1177/15347354241308857.
Sleep disturbance and insomnia are common adverse events in patients with breast cancer (BC). Traditional Chinese Medicine (TCM) treatment for sleep disturbance includes acupuncture, acupressure, auricular acupressure/auricular acupuncture, and Qigong. However, the specific efficacy of these TCM treatment remains unclear.
This systematic review and network meta-analysis (NMA) investigated the effects of various TCM treatment on improving sleep quality in BC survivors.
Only randomized controlled trials (RCTs) reporting the results of TCM treatments were included. The main NMA included 12 RCTs involving 1011 participants. The risk of bias was assessed using the RoB 2 tool for randomized controlled trials. The certainty of evidence of the NMA was assessed in accordance with GRADE (the Grading of Recommendations, Assessment, Development, and Evaluations).
Acupressure, acupuncture, auricular acupuncture/auricular acupressure, and qigong were identified as optimal TCM treatment (P < .05) for enhancing sleep quality in BC survivors.
Our results provide some evidence that TCM treatment, particularly acupressure, can be beneficial in improving sleep quality in BC survivors. However, larger-scale clinical trials with robust methodological designs are required to validate and extend our findings.
睡眠障碍和失眠是乳腺癌（BC）患者常见的不良事件。中医治疗睡眠障碍的方法包括针灸、指压、耳穴按压/耳针和气功。然而，这些中医治疗方法的具体疗效仍不明确。
本系统评价和网络荟萃分析（NMA）研究了各种中医治疗方法对改善BC幸存者睡眠质量的影响。
仅纳入报告中医治疗结果的随机对照试验（RCT）。主要的NMA纳入了12项涉及1011名参与者的RCT。使用随机对照试验的RoB 2工具评估偏倚风险。根据GRADE（推荐分级、评估、制定和评价）对NMA证据的确定性进行评估。
指压、针灸、耳针/耳穴按压和气功被确定为改善BC幸存者睡眠质量的最佳中医治疗方法（P < 0.05）。
我们的结果提供了一些证据，表明中医治疗，特别是指压，可能有助于改善BC幸存者的睡眠质量。然而，需要更大规模、方法设计严谨的临床试验来验证和扩展我们的发现。
