Ma Shengbiao, Zhou Zhenhai, Yu Honggui, Zhong Junlong, Xiong Jiachao, Xu Jiang, Deng Wenqiang, Cao Kai
The Orthopedic Hospital, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Global Spine J. 2024 Apr;14(3):812-820. doi: 10.1177/21925682221123321. Epub 2022 Aug 21.
Retrospective cohort.
To compare outcomes of posterior osteotomized debridement (OD) with combined anterior and posterior approach (AP) in treating thoracolumbar tuberculosis (TB).
This study reviewed 178 patients who were diagnosed as active thoracolumbar TB and surgically treated in our center. One hundred and two patients underwent posterior OD, interbody fusion with titanium mesh cage (TMC), and instrumentation (group A). Seventy-six patients underwent one-stage posterior instrumentation, anterior debridement, and interbody fusion with TMC (group B). Patients' clinical outcomes were compared between the 2 groups.
Erythrocyte sedimentation rate and C-reactive protein in all patients returned to normal levels within 3 months after surgery, and no recurrence occurred during the follow-up. Compared with AP approach, OD surgery was less invasive and with a lower cost (¥ 70 581 ± 17 645 vs ¥ 87 600 ± 27 328; < .05). Patients treated by OD showed more significant improvements in Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) than those treated by AP approach 3 months postoperatively (VAS: 3.0 ± .7 vs 3.7 ± .9; ODI: 14.7 ± 4.4 vs 20.6 ± 4.6). Two groups showed similar postoperative kyphosis correction and final follow-up correction loss ( = .361 and = .162, respectively). The OD method had a lower complication rate than AP approach (9.8% [10/102] vs 35.5% [27/76]; < .05).
Posterior OD is effective in treating active thoracolumbar TB. Compared with traditional AP approach, OD surgery has less surgical invasiveness, lower complication rate, and shorter fusion time.
回顾性队列研究。
比较后路截骨清创术(OD)与前后联合入路(AP)治疗胸腰椎结核(TB)的疗效。
本研究回顾了178例在我院被诊断为活动性胸腰椎结核并接受手术治疗的患者。102例患者接受了后路OD、钛网笼(TMC)椎间融合及内固定术(A组)。76例患者接受了一期后路内固定、前路清创及TMC椎间融合术(B组)。比较两组患者的临床疗效。
所有患者术后3个月内红细胞沉降率和C反应蛋白恢复正常水平,随访期间无复发。与AP入路相比,OD手术创伤更小,费用更低(70581±17645元对87600±27328元;P<0.05)。术后3个月,OD治疗的患者在视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI)方面的改善比AP入路治疗的患者更显著(VAS:3.0±0.7对3.7±0.9;ODI:14.7±4.4对20.6±4.6)。两组术后后凸畸形矫正及末次随访时矫正丢失情况相似(分别为P=0.361和P=0.162)。OD方法的并发症发生率低于AP入路(9.8%[10/102]对35.5%[27/76];P<0.05)。
后路OD治疗活动性胸腰椎结核有效。与传统AP入路相比,OD手术创伤小、并发症发生率低、融合时间短。