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单节段胸椎结核前路与后路清创融合术:植骨类型和固定节段对手术疗效的影响

Anterior versus posterior debridement fusion for single-level dorsal tuberculosis: the role of graft-type and level of fixation on determining the outcome.

作者信息

Assaghir Yasser M, Refae Hesham Hamed, Alam-Eddin Mohamed

机构信息

Orthopaedic Department, Sohag Faculty of Medicine, Sohag University, Sohâg, 82425, Egypt.

Orthopaedic Department, Qena Faculty of Medicine, Qena University, Qena, 98379, Egypt.

出版信息

Eur Spine J. 2016 Dec;25(12):3884-3893. doi: 10.1007/s00586-016-4516-2. Epub 2016 Mar 17.

Abstract

PURPOSE

This study compared the clinical, radiological and functional outcome of anterior versus posterior approaches for single-level dorsal tuberculosis with analysis of effect of graft type and fixation level on the outcome.

METHODS

Anterior group (AG): 43 cases (mean age: 49.5 years) fixed with Z-plate by anterior transthoracic-transpleural approach. Posterior group (PG): 49 cases (47.0 years) fixed with transpedicular-screws with unilateral facetectomy ± pediculectomy. Assessment was done using Frankel classification, blood-loss, operative-time, Kyphus-angle, correction loss, union and Oswestry disability index (ODI).

RESULTS

Both groups had similar operative-time, blood-loss, time to union, follow-up, and hospital-stay. Kyphus-angle improved from 36.6 ± 8.4° to 7.5 ± 2.3° (AG) and from 38.5 ± 5.9° to 11.1 ± 3.6° (PG) and this was significant. Postoperative Kyphus-angles were significantly better than preoperative ones in both groups. The correction percentage was 79.2 % (AG) and 69.9 % (PG) and this was significant. ODI was 3.4 ± 4.1 (AG) and 3.0 ± 4.2 % (PG) and this was insignificant. Correction loss was .8 ± 1.2° (AG) and 1.9 ± 2.2° (PG) and this was significant. Union was faster with iliac graft but with lower correction degree and higher correction loss than rib-strut graft. All patients achieved union. All but three patients achieved full neurological recovery. Superficial infection occurred in three cases (PG:2; AG:1) lung parenchymal injury in two case (AG), and DVT in one case (AG).

CONCLUSIONS

Both approaches give very good union and kyphosis correction rate that were maintained overtime. Anterior approach gives statistically better kyphosis correction and less correction-loss, but this is clinically insignificant. Besides, it is more risky and difficult. Strut-graft is essential in reconstruction and correction of kyphosis and vertebral height.

LEVEL OF EVIDENCE

III therapeutic.

摘要

目的

本研究比较了前路与后路治疗单节段胸椎结核的临床、影像学及功能结果,并分析了植骨类型和固定节段对结果的影响。

方法

前路组(AG):43例(平均年龄:49.5岁),采用经胸-经胸膜前路入路,用Z形钢板固定。后路组(PG):49例(47.0岁),采用经椎弓根螺钉固定,行单侧小关节突切除术±椎弓根切除术。采用Frankel分级、失血量、手术时间、后凸角、矫正丢失、融合情况及Oswestry功能障碍指数(ODI)进行评估。

结果

两组在手术时间、失血量、融合时间、随访时间及住院时间方面相似。后凸角从36.6±8.4°改善至7.5±2.3°(AG组),从38.5±5.9°改善至11.1±3.6°(PG组),差异有统计学意义。两组术后后凸角均显著优于术前。矫正率分别为79.2%(AG组)和69.9%(PG组),差异有统计学意义。ODI分别为3.4±4.1(AG组)和3.0±4.2%(PG组),差异无统计学意义。矫正丢失分别为0.8±1.2°(AG组)和1.9±2.2°(PG组),差异有统计学意义。髂骨植骨融合更快,但矫正程度较低,矫正丢失高于肋骨支撑植骨。所有患者均实现融合。除3例患者外,所有患者均实现完全神经功能恢复。浅表感染3例(PG组2例;AG组1例),肺实质损伤2例(AG组),深静脉血栓形成1例(AG组)。

结论

两种手术方式均能获得良好的融合及后凸矫正率,且长期维持。前路手术在统计学上后凸矫正效果更好,矫正丢失更少,但临床意义不大。此外,前路手术风险更高、难度更大。支撑植骨对于后凸及椎体高度的重建和矫正至关重要。

证据水平

III级治疗性。

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