Ophthalmology Department, Mater Misericordiae University Hospital, Dublin, Ireland.
Histopathology Department, Mater Misericordiae University Hospital, Dublin, Ireland.
Ir J Med Sci. 2023 Jun;192(3):1059-1064. doi: 10.1007/s11845-022-03133-4. Epub 2022 Aug 22.
To review the distribution of histopathological diagnoses and visual outcome of orbital biopsy in an Irish tertiary referral centre over a 10-year period.
This was a retrospective, clinical-histopathological case series. Clinical records of all patients who underwent orbital biopsy between January 2008 and January 2018 in the Mater Misericordiae University Hospital were reviewed using data collected from theatre logbooks and hospital-based medical records.
A total of 83 orbital biopsies in 77 patients were included for analysis in this study. The mean age was 55.7 ± 18.41 years. The mean follow-up period was 1.87 ± 2.097 years. The most common presenting symptoms and signs were pain (22.3%) and proptosis (27.6%). Most lesions were located in the extraconal space (65%), with incisional biopsy (65%) being the most common technique used to gain a sample for histopathological diagnosis. Histopathology analysis of the biopsies revealed malignant tumours (27, 32.5%), benign tumours (7, 8.4%), inflammation (26, 31.3%), and other diagnoses (23, 27%). Excluding patients who underwent exenteration procedures, no study patients suffered visual loss following orbital biopsy.
Orbital biopsy serves as a safe diagnostic tool in managing orbital diseases. The breakdown of diagnosis in our patients is in line with international studies. No patients in our series suffered vision loss as a result of their orbital biopsy. This emphasises its use as a safe procedure in the diagnosis and management of patients with the orbital disease. Our data provides helpful guidance to clinicians when counselling patients for orbital biopsy.
回顾 10 年来爱尔兰一家三级转诊中心的眼眶活检组织病理学诊断分布和视觉结果。
这是一项回顾性的临床病理病例系列研究。通过从手术室日志和医院病历中收集的数据，对 2008 年 1 月至 2018 年 1 月期间在圣母慈悲大学医院接受眼眶活检的所有患者的临床记录进行了回顾。
本研究共纳入 77 例 83 例眼眶活检患者。平均年龄为 55.7±18.41 岁。平均随访时间为 1.87±2.097 年。最常见的临床表现为疼痛（22.3%）和眼球突出（27.6%）。大多数病变位于眶外（65%），最常用的活检技术是切开活检（65%），以获取组织病理学诊断样本。活检组织病理学分析显示恶性肿瘤（27 例，32.5%）、良性肿瘤（7 例，8.4%）、炎症（26 例，31.3%）和其他诊断（23 例，27%）。排除接受眼眶切除术的患者，没有研究患者在眼眶活检后出现视力丧失。
眼眶活检是一种安全的诊断工具，可用于治疗眼眶疾病。我们患者的诊断分类与国际研究一致。我们的研究系列中没有患者因眼眶活检而导致视力丧失。这强调了它作为一种安全的程序，用于诊断和管理患有眼眶疾病的患者。我们的数据为临床医生为眼眶活检患者提供咨询时提供了有用的指导。
