Seregard S, Sahlin S
St. Erik's Eye Hospital and Karolinska Institute, Stockholm, Sweden.
Acta Ophthalmol Scand. 1999 Feb;77(1):91-8. doi: 10.1034/j.1600-0420.1999.770121.x.
The aim of this survey was to study the frequency and management of orbital lesions requiring incisional or excisional biopsy for diagnostic or therapeutic purposes.
A histopathological review of specimens from 300 consecutive patients with space-occupying orbital lesions managed over a period of 24 years at a tertiary referral centre.
The lesions could be attributed to 73 different entities with low-grade, non-Hodgkin lymphoma being the most common. More than half (54.3%) of lesions were neoplastic and malignant disease was present in 29.0% of patients. The majority of lesions were biopsied using the anterior transseptal or transconjunctival approach.
Most orbital space-occupying lesions requiring biopsy are benign and easily accessible. However, the diversity of these rare lesions and complexity of management suggest that patient care is best provided by a team of experienced subspecialists at a designated orbital centre.
本调查旨在研究因诊断或治疗目的而需要进行切开活检或切除活检的眼眶病变的发生率及处理方法。
对一家三级转诊中心在24年期间收治的300例连续性眼眶占位性病变患者的标本进行组织病理学回顾。
这些病变可归因于73种不同的疾病实体，其中低度非霍奇金淋巴瘤最为常见。超过一半（54.3%）的病变为肿瘤性病变，29.0%的患者患有恶性疾病。大多数病变采用经前间隔或经结膜入路进行活检。
大多数需要活检的眼眶占位性病变是良性的且易于处理。然而，这些罕见病变的多样性和处理的复杂性表明，由经验丰富的专科医生团队在指定的眼眶中心提供患者护理是最佳选择。
