Howe Lindy K, Bailey Allen J, Ingram Polly F, Finn Peter R
Department of Psychological & Brain Sciences, Indiana University Bloomington, IN 47405, USA.
Department of Psychological & Brain Sciences, Indiana University Bloomington, IN 47405, USA.
Addict Behav. 2022 Dec;135:107465. doi: 10.1016/j.addbeh.2022.107465. Epub 2022 Aug 17.
Since the release of the DSM-V, CUD has been understood as a unidimensional construct. However, continued research has identified separate symptom clusters relating to consumption, loss of control, and withdrawal within substance use disorder criteria that may pose separate risk factors and functional difficulties. The current study aims to examine how symptom clusters commonly manifest in young adults that use cannabis using a latent class analysis (LCA) and explore how these clusters are related to co-occurring psychological constructs.
1174 (aged 18-34) participants completed a battery of assessments on substance use and other psychological constructs. LCA was conducted on 17 symptoms corresponding with DSM-V CUD criteria. Multinomial regressions were used to examine class membership and commonly co-occurring psychopathology and psychological constructs.
LCA results identified a 'No problems' class, a 'Moderate consumption' class characterized by moderate probability of endorsing consumption items, a 'Consumption with Moderate Loss of Control' class, characterized by endorsing consumption and loss of control items but minimal endorsement of withdrawal items, a 'Consumption with Moderate Withdrawal' class characterized by moderate probability of endorsing all item types, and 'High Consumption, Loss of Control, Withdrawal' class characterized by high probability of endorsing all items. Multinomial regressions indicated some class differences in psychological constructs.
Symptom clusters differed in terms of CUD criteria, especially for those in our sample with moderate/severe problems. Findings suggest intervention efforts may benefit from treatment targeted at various presentations of CUD.
自《精神疾病诊断与统计手册》第五版（DSM-V）发布以来，大麻使用障碍（CUD）一直被视为一种单维结构。然而，持续的研究已经在物质使用障碍标准中识别出与消费、失控和戒断相关的不同症状群，这些症状群可能构成不同的风险因素和功能障碍。本研究旨在使用潜在类别分析（LCA）来检验症状群在使用大麻的年轻成年人中通常是如何表现的，并探讨这些症状群与共病心理结构之间的关系。
1174名（年龄在18 - 34岁之间）参与者完成了一系列关于物质使用和其他心理结构的评估。对与DSM-V CUD标准相对应的17种症状进行了潜在类别分析。使用多项回归来检验类别归属以及常见的共病精神病理学和心理结构。
潜在类别分析结果识别出一个“无问题”类别、一个以认可消费项目的中等概率为特征的“中等消费”类别、一个以认可消费和失控项目但对戒断项目的认可最少为特征的“伴有中等失控的消费”类别、一个以认可所有项目类型的中等概率为特征的“伴有中等戒断的消费”类别，以及一个以认可所有项目的高概率为特征的“高消费、失控、戒断”类别。多项回归表明在心理结构方面存在一些类别差异。
症状群在CUD标准方面存在差异，特别是对于我们样本中存在中度/重度问题的那些人。研究结果表明，干预措施可能会从针对CUD各种表现形式的治疗中受益。
