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在复杂脊柱手术的术后加速康复方案中纳入血液和液体管理

Incorporation of Blood and Fluid Management Within an Enhanced Recovery after Surgery Protocol in Complex Spine Surgery.

作者信息

Yokoi Hana, Chakravarthy Vikram, Winkleman Robert, Manlapaz Mariel, Krishnaney Ajit

机构信息

Department of Neurosurgery, Cleveland Clinic, Cleveland OH, USA.

Case Western Reserve University School of Medicine, Cleveland, OH, USA.

出版信息

Global Spine J. 2024 Mar;14(2):639-646. doi: 10.1177/21925682221120399. Epub 2022 Aug 23.

Abstract

STUDY DESIGN

retrospective review.

OBJECTIVE

Enhanced Recovery After Surgery (ERAS) is a multidisciplinary set of evidence-based interventions to reduce morbidity and accelerate postoperative recovery. Complex spine surgery carries high risks of perioperative blood loss, blood transfusion, and suboptimal fluid states. This study evaluates the efficacy of a perioperative fluid and blood management component comprised of a restrictive transfusion policy, goal directed fluid management, number of tranexamic acid (TXA) utilization, and autologous blood transfusion within our ERAS protocol for complex spine surgery.

METHODS

A retrospective review compared patients undergoing elective complex spine surgery prior to and following implementation of an ERAS protocol with intraoperative blood and fluid management. Outcomes included incidence of blood transfusion, estimated blood loss, intraoperative crystalloids administered, frequency of intraoperative TXA utilized, incidence of patients extubated within the operating room (OR), intensive care unit (ICU) admission, and hospital length of stay.

RESULTS

Following implementation, the rate of blood transfusion decreased by 11.7%( = .017) and average crystalloid infusion was reduced 680 mL per case( < .001). Intraoperative blood loss decreased on average 342 mL per case( = .001) and TXA use increased significantly by 25%( < .001). Postoperative ICU admissions declined by 8.5%( = .071); extubation within the OR increased by 13.3%( = .005).

CONCLUSIONS

This protocol presents a unique perspective with the inclusion of an interdisciplinary and comprehensive blood and fluid management protocol as an integral part of our ERAS pathway for complex spine surgery. These results indicate that a standardized approach is associated with reduced rates of blood transfusion and optimized fluid states which was correlated with decreased postoperative ICU admissions.

摘要

研究设计

回顾性研究。

目的

术后加速康复(ERAS)是一套多学科的循证干预措施,旨在降低发病率并加速术后康复。复杂脊柱手术具有围手术期失血、输血及液体状态不佳的高风险。本研究评估了围手术期液体与血液管理方案的疗效,该方案包括限制性输血策略、目标导向性液体管理、氨甲环酸(TXA)的使用次数以及在我们针对复杂脊柱手术的ERAS方案中的自体输血。

方法

一项回顾性研究比较了在实施ERAS方案并进行术中血液和液体管理前后接受择期复杂脊柱手术的患者。结果包括输血发生率、估计失血量、术中输注晶体液量、术中使用TXA的频率、在手术室(OR)拔管的患者发生率、重症监护病房(ICU)入住率以及住院时间。

结果

实施后,输血率下降了11.7%(P = .017),平均每例晶体液输注量减少了680 mL(P < .001)。术中平均失血量每例减少342 mL(P = .001),TXA的使用显著增加了25%(P < .001)。术后ICU入住率下降了8.5%(P = .071);在手术室拔管率增加了13.3%(P = .005)。

结论

该方案提供了一个独特的视角,即将跨学科和全面的血液与液体管理方案纳入我们针对复杂脊柱手术的ERAS路径中。这些结果表明,标准化方法与输血率降低和液体状态优化相关,这与术后ICU入住率降低相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7d/10802530/a1e383732c4e/10.1177_21925682221120399-fig1.jpg

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