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慢性下腰痛12个月内的疼痛与功能恢复:对整骨医学的启示

Pain and functional recovery from chronic low back pain over 12 months: implications for osteopathic medicine.

作者信息

Licciardone John C, Pandya Vishruti

机构信息

The Osteopathic Research Center and Department of Family Medicine, University of North Texas Health Science Center, Fort Worth, TX, USA.

University of Alabama at Birmingham, Birmingham, AL, USA.

出版信息

J Osteopath Med. 2022 Aug 24;122(12):623-630. doi: 10.1515/jom-2021-0288. eCollection 2022 Dec 1.

Abstract

CONTEXT

Although low back pain is a common medical condition that often progresses to become a chronic problem, little is known about the likelihood of recovery from chronic low back pain (CLBP).

OBJECTIVES

This study aimed to measure the risk of recovery from CLBP based on low back pain intensity and back-related functioning measures reported by participants within a pain research registry over 12 months of observation and to consider the implications for osteopathic medicine.

METHODS

A total of 740 participants with CLBP in the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation in the United States were studied between April 2016 and October 2021. Inception cohorts for pain recovery and functional recovery were assembled from the participants who did not meet the recovery criteria at registry enrollment. The pain recovery criterion was having a score of ≤1/10 on a numerical rating scale for low back pain intensity, and the functional recovery criterion was having a score of ≤4/24 on the Roland-Morris Disability Questionnaire. A total of 737 and 692 participants were included in the inception cohorts for pain recovery and functional recovery, respectively. Participants provided follow-up data at quarterly encounters over 12 months to determine if they achieved and maintained a pain or functional recovery from CLBP over the entire period of observation. Logistic regression was utilized to identify factors associated with recovery.

RESULTS

The mean age of the participants at baseline was 52.9 years (SD, 13.1 years) and 551 (74.5%) were female. No participant reported a pain recovery that was maintained over all four quarterly encounters, whereas 16 participants (2.3%; 95% CI, 1.2-3.4%) maintained a functional recovery. Having high levels of pain self-efficacy (OR, 17.50; 95% CI, 2.30-133.23; p=0.006) and being Hispanic (OR, 3.55; 95% CI, 1.11-11.37; p=0.03) were associated with functional recovery, and high levels of pain catastrophizing (OR, 0.15; 95% CI, 0.03-0.65; p=0.01) and having chronic widespread pain (OR, 0.23; 95% CI, 0.08-0.66; p=0.007) were inversely associated with functional recovery. The findings for pain self-efficacy and Hispanic ethnicity remained significant in the multivariate analysis that adjusted for potential confounders.

CONCLUSIONS

The absence of pain recovery and the low likelihood of functional recovery observed in our study suggests that osteopathic physicians should embrace a biopsychosocial approach to CLBP management and work with patients to set realistic expectations based on more pragmatic outcome measures, such as those that address health-related quality of life. The findings also suggest the potential importance of patient education and counseling to enhance pain self-efficacy.

摘要

背景

虽然腰痛是一种常见的病症,且常常会发展成为慢性问题,但对于慢性腰痛(CLBP)恢复的可能性却知之甚少。

目的

本研究旨在根据疼痛研究登记处参与者报告的腰痛强度和背部相关功能指标,衡量12个月观察期内CLBP恢复的风险,并探讨其对整骨医学的意义。

方法

2016年4月至2021年10月期间,对美国流行病学、临床、介入研究与创新疼痛登记处的740名CLBP患者进行了研究。疼痛恢复和功能恢复的起始队列由登记入组时未达到恢复标准的参与者组成。疼痛恢复标准为腰痛强度数字评分量表得分≤1/10,功能恢复标准为罗兰·莫里斯残疾问卷得分≤4/24。疼痛恢复和功能恢复的起始队列分别纳入了737名和692名参与者。参与者在12个月内每季度随访一次,以确定他们在整个观察期内是否实现并维持了CLBP的疼痛或功能恢复。采用逻辑回归分析确定与恢复相关的因素。

结果

参与者基线时的平均年龄为52.9岁(标准差13.1岁),551名(74.5%)为女性。没有参与者报告在所有四个季度随访中都维持了疼痛恢复,而16名参与者(2.3%;95%CI,1.2 - 3.4%)维持了功能恢复。疼痛自我效能感高(比值比[OR],17.50;95%CI,2.30 - 133.23;p = 0.006)和为西班牙裔(OR,3.55;95%CI,1.11 - 11.37;p = 0.03)与功能恢复相关,而疼痛灾难化程度高(OR,0.15;95%CI,0.03 - 0.65;p = 0.01)和患有慢性广泛性疼痛(OR,0.23;95%CI,0.08 - 0.6

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