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The Relationship between Gastrointestinal Health, Micronutrient Concentrations, and Autoimmunity: A Focus on the Thyroid.胃肠道健康、微量营养素浓度与自身免疫之间的关系:重点关注甲状腺。
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Quality of life and sleep in individuals with irritable bowel syndrome according to different diagnostic criteria and inflammatory bowel diseases: A comparison using data from a population-based survey.根据不同的诊断标准和炎症性肠病,比较个体的生活质量和睡眠在肠易激综合征和炎症性肠病中的表现:基于人群调查数据的比较。
Z Gastroenterol. 2022 Mar;60(3):299-309. doi: 10.1055/a-1708-0277. Epub 2022 Mar 9.
2
Elevated Levels of Circulating Biomarkers Related to Leaky Gut Syndrome and Bacterial Translocation Are Associated With Graves' Disease.循环生物标志物水平升高与漏肠综合征和细菌易位相关,与格雷夫斯病有关。
Front Endocrinol (Lausanne). 2021 Dec 16;12:796212. doi: 10.3389/fendo.2021.796212. eCollection 2021.
3
Transient high thyroid stimulating hormone and hypothyroidism incidence during follow up of subclinical hypothyroidism.亚临床甲状腺功能减退症随访中一过性高促甲状腺激素血症和甲状腺功能减退症的发生率。
Endocr Regul. 2021 Dec 7;55(4):204-214. doi: 10.2478/enr-2021-0022.
4
Efficacy and Safety of Rifaximin Versus Placebo or Other Active Drugs in Critical ill Patients With Hepatic Encephalopathy.利福昔明对比安慰剂或其他活性药物治疗重症肝性脑病患者的疗效和安全性
Front Pharmacol. 2021 Oct 8;12:696065. doi: 10.3389/fphar.2021.696065. eCollection 2021.
5
Psychological and Gastrointestinal Symptoms of Patients with Irritable Bowel Syndrome Undergoing a Low-FODMAP Diet: The Role of the Intestinal Barrier.肠易激综合征患者行低 FODMAP 饮食治疗后出现的心理和胃肠道症状:肠道屏障的作用。
Nutrients. 2021 Jul 19;13(7):2469. doi: 10.3390/nu13072469.
6
Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials.左甲状腺素治疗老年人亚临床甲状腺功能减退症与心血管结局:两项随机对照试验的汇总个体结果。
Front Endocrinol (Lausanne). 2021 May 20;12:674841. doi: 10.3389/fendo.2021.674841. eCollection 2021.
7
Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis.停止甲状腺激素替代治疗后的临床结局:系统评价和荟萃分析。
Thyroid. 2021 May;31(5):740-751. doi: 10.1089/thy.2020.0679. Epub 2020 Dec 29.
8
Short-course Rifaximin therapy efficacy and lactulose hydrogen breath test in Chinese patients with diarrhea-predominant irritable bowel syndrome.利福昔明短程疗法疗效及乳果糖氢呼气试验在腹泻型肠易激综合征中国患者中的应用。
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The efficacy and safety of probiotics for patients with constipation-predominant irritable bowel syndrome: A systematic review and meta-analysis based on seventeen randomized controlled trials.益生菌治疗便秘型肠易激综合征患者的疗效和安全性:基于十七项随机对照试验的系统评价和荟萃分析。
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Improving Hashimoto's thyroiditis by eradicating : Relation to IL-17.通过根除改善桥本甲状腺炎:与白细胞介素-17的关系
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最初归因于甲状腺功能障碍的症状实际上是由胃肠道健康欠佳引起的:病例系列及文献综述

Symptoms Originally Attributed to Thyroid Dysfunction Were Instead Caused by Suboptimal Gastrointestinal Health: A Case Series and Literature Review.

作者信息

Ruscio Michael, Guard Gavin, Mather Joe

机构信息

Ruscio Institute is based in Austin, Texas.

出版信息

Integr Med (Encinitas). 2022 Jul;21(3):22-29.

PMID:35999903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9380837/
Abstract

The integrative and functional medicine field has drifted towards a thyroid-centric approach of care (fine-tune thyroid medication, support thyroid hormone conversion, and improve thyroid levels). However, many patients still do not improve symptomatically. Here, we show how a gut-focused clinical care model can improve thyroid function, reduce thyroid medication dose, and improve symptoms originally thought to be from thyroid dysfunction. We present a literature review on the gutthyroid axis and then document clinical application of this evidence through six case reports of how patients improved thyroid function and thyroid-related symptoms by improving their gastrointestinal health. Clinicians will likely experience better patient outcomes by integrating the contents of this paper into their practice.

摘要

整合医学和功能医学领域已倾向于以甲状腺为中心的治疗方法(微调甲状腺药物、支持甲状腺激素转化并改善甲状腺水平)。然而,许多患者的症状仍未改善。在此,我们展示了一种以肠道为重点的临床护理模式如何改善甲状腺功能、降低甲状腺药物剂量,并改善原本认为由甲状腺功能障碍引起的症状。我们对肠-甲状腺轴进行了文献综述,然后通过六个病例报告记录了这一证据的临床应用,这些病例报告展示了患者如何通过改善胃肠道健康来改善甲状腺功能和甲状腺相关症状。临床医生若将本文内容融入其临床实践,可能会获得更好的患者治疗效果。