利用 DNA 的固有荧光探测金属依赖性 G-四链体
Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA.
机构信息
Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
出版信息
Chem Commun (Camb). 2022 Sep 13;58(73):10225-10228. doi: 10.1039/d2cc03967b.
PMID:36001027
Abstract
K enhanced the intrinsic fluorescence of a series of G-quadruplex DNAs, while Pb quenched the fluorescence. The metals showed interesting quadruplex binding kinetics with various DNA sequences.
摘要
钾增强了一系列 G-四链体 DNA 的本征荧光，而铅则猝灭了荧光。这些金属与各种 DNA 序列表现出有趣的四链体结合动力学。
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