Laboratoire des Interactions Plantes-Microbes-Environnement (LIPME), INRAE, CNRS, Université de Toulouse, F-31326 Castanet-Tolosan, France.
Institute for Resistance Research and Stress Tolerance, Federal Research Centre for Cultivated Plants, Julius Kühn-Institute (JKI), Quedlinburg, Germany.
Curr Opin Plant Biol. 2022 Oct;69:102276. doi: 10.1016/j.pbi.2022.102276. Epub 2022 Aug 21.
Plants can detect microbial molecules via surface-localized pattern-recognition receptors (PRRs) and intracellular immune receptors from the nucleotide-binding, leucine-rich repeat receptor (NLR) family. The corresponding pattern-triggered (PTI) and effector-triggered (ETI) immunity were long considered separate pathways, although they converge on largely similar cellular responses, such as calcium influx and overlapping gene reprogramming. A number of studies recently uncovered genetic and molecular interconnections between PTI and ETI, highlighting the complexity of the plant immune network. Notably, PRR- and NLR-mediated immune responses require and potentiate each other to reach an optimal immune output. How PTI and ETI connect to confer robust immunity in different plant species, including crops will be an exciting future research area.
植物可以通过位于表面的模式识别受体（PRRs）以及来自核苷酸结合、富含亮氨酸重复受体（NLR）家族的细胞内免疫受体来检测微生物分子。相应的模式触发（PTI）和效应子触发（ETI）免疫长期以来被认为是独立的途径，尽管它们在很大程度上趋同于相似的细胞反应，如钙离子内流和重叠的基因重编程。最近的许多研究揭示了 PTI 和 ETI 之间的遗传和分子联系，突显了植物免疫网络的复杂性。值得注意的是，PRR 和 NLR 介导的免疫反应需要相互促进，以达到最佳的免疫效果。PTI 和 ETI 如何连接以赋予不同植物物种（包括作物）强大的免疫力将是一个令人兴奋的未来研究领域。
