Stepanenko V F, Norets T A, Dedov V I
Med Radiol (Mosk). 1987 Jun;32(6):45-9.
The paper is concerned with some data on mean absorbed dose values in the animals' organs, the time course of their formation and the character of microdistribution of an absorbed dose around thyroid follicles in internal irradiation of the rat body with 131I and 125I. A raised level of irradiation of the animals' pituitary body is noted. The authors provide dosimetric characteristics of irradiation of thyroid microstructures noting that 125I creates more inhomogeneous distribution of an absorbed dose around thyroid follicles compared to 131I, irradiating, to a greater extent, the follicular membrane and, to a lesser degree, the nuclei of surrounding cells whereas 131I provides homogeneous irradiation of thyroid cells. The authors give a comparative critical analysis of the quantitative and microdosimetric characteristics and literature data.
该论文涉及大鼠体内用131I和125I进行内照射时，动物器官中平均吸收剂量值的一些数据、其形成的时间进程以及甲状腺滤泡周围吸收剂量的微观分布特征。注意到动物垂体的照射水平有所提高。作者提供了甲状腺微观结构的剂量学特征，指出与131I相比，125I在甲状腺滤泡周围产生的吸收剂量分布更不均匀，在更大程度上照射滤泡膜，而对周围细胞核的照射程度较小，而131I能均匀照射甲状腺细胞。作者对定量和微观剂量学特征以及文献数据进行了比较批判性分析。
