消化道红细胞小体炎症监测：病例报告及文献复习。
Surveillance of Russell body inflammation of the digestive tract: a case report and review of literature.
机构信息
Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, P.R. China.
出版信息
Diagn Pathol. 2022 Aug 25;17(1):67. doi: 10.1186/s13000-022-01242-3.
INTRODUCTION
Russell body inflammation of the digestive tract (RBIDT) is a rare chronic inflammation of the digestive tract mucosa that commonly presents as Russell body gastritis (RBG). This disease is usually associated with Helicobacter pylori (HP) infection. However, it can also occur in individuals without HP infection and with specific immune profiles, as seen in HIV and hepatitis C infections. The aetiology and pathogenesis of this disease remain controversial. Given the rarity of the disease and the diversity of the immunophenotypes, there is a high probability of misdiagnosis.
CASE PRESENTATION
A male patient with RBG and HP infection was included in this study. The case of RBG with an unusual morphology of Mott cells that mimics stamped ring cells.Endoscopy performed during the follow-up revealed regression of the lesion 1 week after anti-HP treatment.
CONCLUSIONS
A case of RBG with a high likelihood of misdiagnosis of signet ring cell carcinoma (SRC) has been reported in this study along with a review of the relevant literature and an overview of RBIDT.
简介
肠道 Russell 体炎症（RBIDT）是一种罕见的慢性消化道黏膜炎症，通常表现为 Russell 体胃炎（RBG）。这种疾病通常与幽门螺杆菌（HP）感染有关。然而，它也可能发生在没有 HP 感染且具有特定免疫表型的个体中，如 HIV 和丙型肝炎感染。该疾病的病因和发病机制仍存在争议。鉴于该疾病的罕见性和免疫表型的多样性，误诊的可能性很高。
病例介绍
本研究纳入了一名 RBG 合并 HP 感染的男性患者。该病例的 Mott 细胞形态异常，类似于印戒细胞，为 RBG 中的不常见形态。在 HP 治疗后 1 周进行的内镜检查显示病变消退。
结论
本研究报告了一例 RBG 病例，高度可能误诊为印戒细胞癌（SRC），并对相关文献进行了复习，概述了 RBIDT。
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