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丹麦北部地区医院的COVID-19接触者追踪:一项回顾性研究。

COVID-19 contact tracing in the hospitals located in the North Denmark region: A retrospective review.

作者信息

Fromberg Dorte, Ank Nina, Nielsen Hans L

机构信息

Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.

Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

出版信息

J Infect Prev. 2022 Sep;23(5):228-234. doi: 10.1177/17571774221107754. Epub 2022 Jun 17.

Abstract

BACKGROUND

The Department of Infection Control, at our University Hospital conducted contact tracing of COVID-19 positive patients and staff members at all hospitals in the North Denmark Region.

AIM

To describe the contact tracing performed during the COVID-19 pandemic in the Region and its outcomes.

METHODS

Data from each contact tracing were collected prospectively during 14 May 2020-26 May 2021. Data included information about the index case (patient or hospital staff member), presentation (asymptomatic vs symptomatic), probable source of transmission (community-acquired or hospital-acquired), number of close contacts and if any of these were SARS-CoV-2 PCR-test positive.

FINDINGS

362 contact tracing were performed. A total of 573 COVID-19 positive cases were identified among 171 (30%) patients and 402 (70%) staff members. 192 (34%) of all cases were tested due to symptoms of COVID-19, whereas two-third were tested for other reasons including outbreak and systematic screening tests. A total of 1575 close contacts were identified, including 225 (14%) patients and 1350 (86%) staff members. 100 (6%) close contacts, including 24 patients and 76 staff members, were infected with SARS-CoV-2, of which 33 (43%) staff members was positive at day 0 i.e. the same day as being identified as close contacts.

DISCUSSION

We found a three to one of close contacts to each index case, but only 6% became SARS-CoV-2 positive, with a surprisingly high number of those identified at day 0. Our data confirm that regular testing of patients and staff will identify asymptomatic carriers and thereby prevent new cases.

摘要

背景

我校附属医院感染控制部门对北丹麦地区所有医院的新冠病毒检测呈阳性的患者和工作人员进行了接触者追踪。

目的

描述该地区在新冠疫情期间进行的接触者追踪及其结果。

方法

前瞻性收集了2020年5月14日至2021年5月26日期间每次接触者追踪的数据。数据包括索引病例(患者或医院工作人员)的信息、临床表现(无症状与有症状)、可能的传播源(社区获得性或医院获得性)、密切接触者数量以及这些密切接触者中是否有新冠病毒核酸检测呈阳性。

结果

共进行了362次接触者追踪。在171名(30%)患者和402名(70%)工作人员中,共识别出573例新冠病毒检测呈阳性的病例。所有病例中有192例(34%)因新冠病毒症状接受检测,而三分之二是因包括疫情爆发和系统筛查检测等其他原因接受检测。共识别出1575名密切接触者,包括225名(14%)患者和1350名(86%)工作人员。100名(6%)密切接触者感染了新冠病毒,其中包括24名患者和76名工作人员,其中33名(43%)工作人员在第0天即被确定为密切接触者的同一天呈阳性。

讨论

我们发现每个索引病例的密切接触者与病例数之比为三比一,但只有6%的密切接触者新冠病毒检测呈阳性,其中在第0天被识别出的人数惊人地多。我们的数据证实,对患者和工作人员进行定期检测将识别出无症状携带者,从而预防新病例的出现。

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本文引用的文献

1
The effectiveness of backward contact tracing in networks.网络中反向接触追踪的有效性。
Nat Phys. 2021 May;17:652-658. doi: 10.1038/s41567-021-01187-2. Epub 2021 Feb 25.
7
Optimal COVID-19 quarantine and testing strategies.最优 COVID-19 隔离和检测策略。
Nat Commun. 2021 Jan 7;12(1):356. doi: 10.1038/s41467-020-20742-8.
10
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis.SARS-CoV-2 的传播和发病机制。
Trends Immunol. 2020 Dec;41(12):1100-1115. doi: 10.1016/j.it.2020.10.004. Epub 2020 Oct 14.

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