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在德克萨斯州休斯顿使用全基因组测序检测A组的传播情况。

Use of whole-genome sequencing to detect transmission of group A in Houston, TX.

作者信息

Alamarat Zain I, Sanson Misu A, McNeil J Chase, Baker Carol J, Flores Anthony R

机构信息

Division of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, TX, USA.

Present address: Division of Infectious Diseases, Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

出版信息

Access Microbiol. 2022 May 19;4(5):acmi000351. doi: 10.1099/acmi.0.000351. eCollection 2022 Aug.

Abstract

We used a combination of local, comprehensive strain surveillance and bacterial whole-genome sequencing to identify potential transmission events of group A streptococcus (GAS) in Houston, TX, USA. We identified pharyngeal and skin and soft tissue sources of infection as having important roles in community GAS transmission, including invasive diseases.

摘要

我们采用了本地综合菌株监测与细菌全基因组测序相结合的方法,以识别美国得克萨斯州休斯敦A群链球菌(GAS)的潜在传播事件。我们确定咽部、皮肤及软组织感染源在社区GAS传播(包括侵袭性疾病)中发挥着重要作用。

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