Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.
Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.
Front Endocrinol (Lausanne). 2022 Aug 8;13:934274. doi: 10.3389/fendo.2022.934274. eCollection 2022.
Occlusal support was proved to be associated with type 2 diabetes. Our aim was to investigate the association between the Eichner index and the prevalence of type 2 diabetes. We included 715 participants with oral health examinations in the Shanghai Aging Study. The occlusal support status was determined by the number of functional occlusal support areas and Eichner index classifications. Those with fasting plasma glucose ≥126 mg/dL and/or hemoglobin A1c ≥6.5% and/or current medications for type 2 diabetes with relevant medical history were diagnosed with type 2 diabetes. Multiple logistic regression models were used to analyze the relationship between occlusal support status and type 2 diabetes. The average age of 715 participants was 73.74 ± 6.49 years old. There were 84 diabetics with 1.71 occlusal supporting areas on average. Seven hundred and fifteen participants were divided into 3 groups according to Eichner classifications: Eichner group A with 4 occlusal functional areas, Eichner group B with 1-3 occlusal functional areas or 0 area with anterior occlusal contact, and Eichner group C with no functional occlusal contact. Blood glucose level was significantly lower in participants of Eichner group A compared to those in group B or C. The ordinal logistic regression showed more occlusal supporting areas were significantly associated with less type 2 diabetes cases with an Odds Ratio(OR) of 0.253(95%CI 0.108-0.594) after adjusting covariates. Participants in Eichner group A had a significantly much lower OR of 0.078 for type 2 diabetes (95%CI 0.009-0.694) compared to those in Eichner group C after adjustment. The number of functional occlusal support areas might be inversely related to the blood glucose level and the prevalence of type 2 diabetes.
咬合支持被证明与 2 型糖尿病有关。我们的目的是研究 Eichner 指数与 2 型糖尿病患病率之间的关系。我们纳入了上海老龄化研究中 715 名接受口腔健康检查的参与者。咬合支持状态通过功能咬合支持区域的数量和 Eichner 指数分类来确定。空腹血糖≥126mg/dL 和/或糖化血红蛋白≥6.5%和/或正在服用 2 型糖尿病药物并有相关病史的参与者被诊断为 2 型糖尿病。多因素逻辑回归模型用于分析咬合支持状态与 2 型糖尿病之间的关系。715 名参与者的平均年龄为 73.74±6.49 岁。84 名糖尿病患者平均有 1.71 个咬合支持区。根据 Eichner 分类，715 名参与者分为 3 组：Eichner 组 A 有 4 个咬合功能区，Eichner 组 B 有 1-3 个咬合功能区或 0 个前牙咬合接触区，Eichner 组 C 没有功能咬合接触。与 Eichner 组 B 或 C 相比，Eichner 组 A 的参与者血糖水平显著降低。有序逻辑回归显示，调整协变量后，更多的咬合支持区与 2 型糖尿病病例显著减少相关，优势比（OR）为 0.253（95%CI 0.108-0.594）。与 Eichner 组 C 相比，调整后 Eichner 组 A 的 2 型糖尿病 OR 显著降低（95%CI 0.009-0.694），为 0.078。功能咬合支持区域的数量可能与血糖水平和 2 型糖尿病的患病率呈负相关。
