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基于价值的系统性治疗:未来之路。

Value-Based Care in Systemic Therapy: The Way Forward.

机构信息

Department of Oncology, MOSC Medical College, Ernakulam 682311, Kerala, India.

Government Medical College, Thrissur 680596, Kerala, India.

出版信息

Curr Oncol. 2022 Aug 16;29(8):5792-5799. doi: 10.3390/curroncol29080456.

DOI:10.3390/curroncol29080456
PMID:36005194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9406978/
Abstract

The rising cost of cancer care has shed light on an important aspect of healthcare delivery. Financial toxicity of therapy must be considered in clinical practice and policy-making. One way to mitigate the impact of financial toxicity of cancer care is by focusing on an approach of healthcare delivery that aims to deliver value to the patient. Should value of therapy be one of the most important determinants of cancer care? If so, how do we measure it? How can we implement it in routine clinical practice? In this viewpoint, we discuss value-based care in systemic therapy in oncology. Strategies to improve the quality of care by incorporating value-based approaches are discussed: use of composite tools to assess the value of drugs, alternative dosing strategies, and the use of Health Technology Assessment in regulatory procedures. We propose that there must be a greater emphasis on value of therapy in determining its use and its cost.

摘要

癌症治疗费用的不断上涨凸显了医疗服务提供的一个重要方面。在临床实践和决策中必须考虑治疗的经济毒性。减轻癌症治疗经济毒性影响的一种方法是关注旨在为患者提供价值的医疗服务提供方法。治疗的价值应该成为癌症护理最重要的决定因素之一吗?如果是这样,我们如何衡量它?我们如何将其实施到常规临床实践中?在本观点中,我们讨论了肿瘤学中系统治疗的基于价值的护理。讨论了通过采用基于价值的方法来提高护理质量的策略:使用综合工具来评估药物的价值、替代剂量策略以及在监管程序中使用卫生技术评估。我们提出,在确定治疗的使用及其成本时,必须更加重视治疗的价值。

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本文引用的文献

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Redefining Health: Implication for Value-Based Healthcare Reform.重新定义健康:对基于价值的医疗改革的启示。
Cureus. 2017 Feb 22;9(2):e1047. doi: 10.7759/cureus.1047. eCollection 2017 Feb.
2
Financial toxicity in cancer care in India: a systematic review.印度癌症护理中的财务毒性:系统评价。
Lancet Oncol. 2021 Dec;22(12):e541-e549. doi: 10.1016/S1470-2045(21)00468-X.
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An urgent call to raise the bar in oncology.呼吁提高肿瘤学水平。
Br J Cancer. 2021 Nov;125(11):1477-1485. doi: 10.1038/s41416-021-01495-7. Epub 2021 Aug 16.
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An assessment of the use of patient reported outcome measurements (PROMs) in cancers of the pelvic abdominal cavity: identifying oncologic benefit and an evidence-practice gap in routine clinical practice.盆腔腹腔癌症患者报告结局测量(PROMs)使用评估:确定常规临床实践中的肿瘤学获益和证据-实践差距。
Health Qual Life Outcomes. 2021 Jan 15;19(1):20. doi: 10.1186/s12955-020-01648-x.
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Cancer Immunotherapy Dosing: A Pharmacokinetic/Pharmacodynamic Perspective.癌症免疫治疗剂量:药代动力学/药效学视角
Vaccines (Basel). 2020 Oct 31;8(4):632. doi: 10.3390/vaccines8040632.
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Cancer J. 2020 Jul/Aug;26(4):311-322. doi: 10.1097/PPO.0000000000000459.
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Medical Care Costs Associated with Cancer Survivorship in the United States.美国癌症生存者相关的医疗保健费用。
Cancer Epidemiol Biomarkers Prev. 2020 Jul;29(7):1304-1312. doi: 10.1158/1055-9965.EPI-19-1534. Epub 2020 Jun 10.
8
The health care cost of palliative care for cancer patients: a systematic review.癌症患者姑息治疗的医疗费用:系统评价。
Support Care Cancer. 2020 Oct;28(10):4561-4573. doi: 10.1007/s00520-020-05512-y. Epub 2020 May 21.
9
Defining and Implementing Value-Based Health Care: A Strategic Framework.定义和实施基于价值的医疗保健:战略框架。
Acad Med. 2020 May;95(5):682-685. doi: 10.1097/ACM.0000000000003122.
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Waste in the US Health Care System: Estimated Costs and Potential for Savings.美国医疗体系中的浪费:估计成本和节约潜力。
JAMA. 2019 Oct 15;322(15):1501-1509. doi: 10.1001/jama.2019.13978.