Hutchinson Institute for Cancer Outcomes Research, Fred Hutchinson Cancer Center, Seattle, WA.
Division of Medical Oncology, University of Washington School of Medicine, Seattle, WA.
J Clin Oncol. 2023 Jun 1;41(16):3051-3058. doi: 10.1200/JCO.22.01799. Epub 2023 Apr 18.
Patients with cancer face an array of financial consequences as a result of their diagnosis and treatment, collectively referred to as financial toxicity (FT). In the past 10 years, the body of literature on this subject has grown tremendously, with a recent focus on interventions and mitigation strategies. In this review, we will briefly summarize the FT literature, focusing on the contributing factors and downstream consequences on patient outcomes. In addition, we will put FT into context with our emerging understanding of the role of social determinants of health and provide a framework for understanding FT across the cancer care continuum. We will then discuss the role of the oncology community in addressing FT and outline potential strategies that oncologists and health systems can implement to reduce this undue burden on patients with cancer and their families.
由于诊断和治疗,癌症患者面临一系列的经济后果,通常被称为财务毒性(Financial Toxicity,FT)。在过去的 10 年中,这方面的文献数量迅速增加,最近的重点是干预和缓解策略。在这篇综述中,我们将简要总结 FT 的文献,重点介绍导致 FT 的因素以及对患者结局的下游影响。此外,我们将把 FT 放在我们对健康社会决定因素作用的理解的背景下,并提供一个贯穿癌症治疗全程的 FT 理解框架。然后,我们将讨论肿瘤学界在解决 FT 方面的作用,并概述肿瘤学家和医疗系统可以实施的潜在策略,以减轻癌症患者及其家庭的这种不必要的负担。