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利用机器学习预测全肩关节置换术后的总医疗费用。

Prediction of total healthcare cost following total shoulder arthroplasty utilizing machine learning.

机构信息

Department of Orthopaedic Surgery, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA.

Department of Orthopedic Surgery, Westchester Medical Center, Valhalla, NY, USA.

出版信息

J Shoulder Elbow Surg. 2022 Dec;31(12):2449-2456. doi: 10.1016/j.jse.2022.07.013. Epub 2022 Aug 22.

Abstract

BACKGROUND

Given the increase in demand in treatment of glenohumeral arthritis with anatomic total (aTSA) and reverse shoulder arthroplasty (RTSA), it is imperative to improve quality of patient care while controlling costs as private and federal insurers continue its gradual transition toward bundled payment models. Big data analytics with machine learning shows promise in predicting health care costs. This is significant as cost prediction may help control cost by enabling health care systems to appropriately allocate resources that help mitigate the cause of increased cost.

METHODS

The Nationwide Readmissions Database (NRD) was accessed in 2018. The database was queried for all primary aTSA and RTSA by International Classification of Diseases, Tenth Revision (ICD-10) procedure codes: 0RRJ0JZ and 0RRK0JZ for aTSA and 0RRK00Z and 0RRJ00Z for RTSA. Procedures were categorized by diagnoses: osteoarthritis (OA), rheumatoid arthritis (RA), avascular necrosis (AVN), fracture, and rotator cuff arthropathy (RCA). Costs were calculated by utilizing the total hospital charge and each hospital's cost-to-charge ratio. Hospital characteristics were included, such as volume of procedures performed by the respective hospital for the calendar year and wage index, which represents the relative average hospital wage for the respective geographic area. Unplanned readmissions within 90 days were calculated using unique patient identifiers, and cost of readmissions was added to the total admission cost to represent the short-term perioperative health care cost. Machine learning algorithms were used to predict patients with immediate postoperative admission costs greater than 1 standard deviation from the mean, and readmissions.

RESULTS

A total of 49,354 patients were isolated for analysis, with an average patient age of 69.9 ± 9.6 years. The average perioperative cost of care was $18,843 ± $10,165. In total, there were 4279 all-cause readmissions, resulting in an average cost of $13,871.00 ± $14,301.06 per readmission. Wage index, hospital volume, patient age, readmissions, and diagnosis-related group severity were the factors most correlated with the total cost of care. The logistic regression and random forest algorithms were equivalent in predicting the total cost of care (area under the receiver operating characteristic curve = 0.83).

CONCLUSION

After shoulder arthroplasty, there is significant variability in cumulative hospital costs, and this is largely affected by readmissions. Hospital characteristics, such as geographic area and volume, are key determinants of overall health care cost. When accounting for this, machine learning algorithms may predict cases with high likelihood of increased resource utilization and/or readmission.

摘要

背景

鉴于解剖型全肩关节置换术(aTSA)和反式肩关节置换术(RTSA)治疗肩关节炎的需求增加,在私人和联邦保险公司逐渐向捆绑支付模式过渡的情况下,提高患者护理质量并控制成本至关重要。机器学习的大数据分析在预测医疗保健成本方面显示出前景。这很重要,因为成本预测可以通过使医疗保健系统能够适当地分配资源来帮助控制成本,从而有助于减轻成本增加的原因。

方法

2018 年访问了全国再入院数据库(NRD)。通过国际疾病分类第十版(ICD-10)程序代码 0RRJ0JZ 和 0RRK0JZ 对所有原发性 aTSA 和 RTSA 进行数据库查询:0RRK00Z 和 0RRJ00Z 用于 RTSA。根据诊断对手术进行分类:骨关节炎(OA)、类风湿性关节炎(RA)、 缺血性坏死(AVN)、骨折和肩袖关节炎(RCA)。通过利用总住院费用和每家医院的成本与收费比来计算成本。包括医院特征,如相应医院在日历年执行的手术量和工资指数,该指数代表相应地理区域的相对平均医院工资。使用唯一的患者标识符计算 90 天内的非计划性再入院,并将再入院费用添加到总入院费用中,以代表短期围手术期医疗保健费用。使用机器学习算法预测术后即刻住院费用超过平均值 1 个标准差的患者,以及再入院患者。

结果

共分析了 49354 例患者,平均患者年龄为 69.9±9.6 岁。围手术期护理费用平均为 18843±10165 美元。共有 4279 例全因再入院,导致平均每次再入院费用为 13871.00±14301.06 美元。工资指数、医院量、患者年龄、再入院和诊断相关组严重程度是与总护理费用最相关的因素。逻辑回归和随机森林算法在预测总护理费用方面等效(接受者操作特征曲线下面积=0.83)。

结论

肩关节置换术后,医院总费用存在显著差异,这在很大程度上受到再入院的影响。医院特征,如地理位置和量,是整体医疗保健成本的关键决定因素。在考虑到这一点的情况下,机器学习算法可以预测高资源利用率和/或再入院可能性的病例。

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