University of Science, Ho Chi Minh City, Vietnam.
Vietnam National University, Ho Chi Minh City, Vietnam.
Nat Prod Res. 2024 Jan-Feb;38(2):327-330. doi: 10.1080/14786419.2022.2113996. Epub 2022 Aug 25.
From an EtOAc-soluble fraction of the roots of , one undescribed chromene derivative, paratrimerin Z (), was isolated. Its structure was elucidated on the basis of NMR spectroscopic interpretation. The absolute configuration of was determined by the specific rotation analysis of its acid-catalyzed hydrolysis product. Paratrimerin Z (), at a concentration of 100 M, did not show cytotoxicity against Hep3B human liver cancer cell line.
从 根的 EtOAc 可溶部分中,分离得到一个未被描述的色烯衍生物,即 paratrimerin Z()。基于 NMR 波谱解释,确定了其结构。通过其酸催化水解产物的比旋光度分析确定了 的绝对构型。Paratrimerin Z()在 100 μM 的浓度下,对 Hep3B 人肝癌细胞系没有显示细胞毒性。